Marine pharmacology in 2018: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral activities; …

AMS Mayer, ML Pierce, K Howe, AD Rodríguez… - Pharmacological …, 2022 - Elsevier
The 2018 marine pharmacology literature review represents a continuation of the previous
11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during …

Ten-year research update review: Antiviral activities from marine organisms

G Riccio, N Ruocco, M Mutalipassi, M Costantini… - Biomolecules, 2020 - mdpi.com
Oceans cover more than 70 percent of the surface of our planet and are characterized by
huge taxonomic and chemical diversity of marine organisms. Several studies have shown …

Enantioselective phosphine-catalyzed [6+ 1] annulations of α-allyl allenoates with 1, 1-bisnucleophiles

J Lai, W Cai, Y Huang - Chemical Science, 2024 - pubs.rsc.org
Organocatalytic annulations between allenes and bisnucleophiles represent one of the most
convenient routes to various carbocycles and heterocycles. However, most examples are …

Marine natural products as leads against SARS-CoV-2 infection

BK Chhetri, PR Tedbury… - Journal of natural …, 2022 - ACS Publications
Since early 2020, disease caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a global pandemic, causing millions of infections and deaths …

NF-κB-interacting long noncoding RNA regulates HIV-1 replication and latency by repressing NF-κB signaling

H Wang, Y Liu, C Huan, J Yang, Z Li, B Zheng… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT NF-κB-interacting long noncoding RNA (NKILA) was recently identified as a
negative regulator of NF-κB signaling and plays an important role in the development of …

Natural product-derived compounds in HIV suppression, remission, and eradication strategies

RJ Andersen, F Ntie-Kang, I Tietjen - Antiviral Research, 2018 - Elsevier
While combination antiretroviral therapy (cART) has successfully converted HIV to a chronic
but manageable infection in many parts of the world, HIV continues to persist within latent …

Identification of novel HIV-1 latency-reversing agents from a library of marine natural products

K Richard, DE Williams, ED De Silva, MA Brockman… - Viruses, 2018 - mdpi.com
Natural products originating from marine and plant materials are a rich source of chemical
diversity and unique antimicrobials. Using an established in vitro model of HIV-1 latency, we …

Marine-Derived Bioactive Metabolites as a Potential Therapeutic Intervention in Managing Viral Diseases: Insights from the SARS-CoV-2 In Silico and Pre-Clinical …

QN Okechukwu, FO Adepoju, ON Kanwugu, P Adadi… - Pharmaceuticals, 2024 - mdpi.com
Worldwide urbanization and subsequent migration have accelerated the emergence and
spread of diverse novel human diseases. Among them, diseases caused by viruses could …

The development of the bengamides as new antibiotics against drug-resistant bacteria

C Porras-Alcalá, F Moya-Utrera, M García-Castro… - Marine Drugs, 2022 - mdpi.com
The bengamides comprise an interesting family of natural products isolated from sponges
belonging to the prolific Jaspidae family. Their outstanding antitumor properties, coupled …

Novel antiretroviral structures from marine organisms

K Wittine, L Saftić, Ž Peršurić, S Kraljević Pavelić - Molecules, 2019 - mdpi.com
In spite of significant advancements and success in antiretroviral therapies directed against
HIV infection, there is no cure for HIV, which scan persist in a human body in its latent form …