Marine pharmacology in 2018: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis and antiviral activities; …
AMS Mayer, ML Pierce, K Howe, AD Rodríguez… - Pharmacological …, 2022 - Elsevier
The 2018 marine pharmacology literature review represents a continuation of the previous
11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during …
11 reviews of a series initiated in 1998. Preclinical marine pharmacology research during …
Ten-year research update review: Antiviral activities from marine organisms
Oceans cover more than 70 percent of the surface of our planet and are characterized by
huge taxonomic and chemical diversity of marine organisms. Several studies have shown …
huge taxonomic and chemical diversity of marine organisms. Several studies have shown …
Enantioselective phosphine-catalyzed [6+ 1] annulations of α-allyl allenoates with 1, 1-bisnucleophiles
J Lai, W Cai, Y Huang - Chemical Science, 2024 - pubs.rsc.org
Organocatalytic annulations between allenes and bisnucleophiles represent one of the most
convenient routes to various carbocycles and heterocycles. However, most examples are …
convenient routes to various carbocycles and heterocycles. However, most examples are …
Marine natural products as leads against SARS-CoV-2 infection
BK Chhetri, PR Tedbury… - Journal of natural …, 2022 - ACS Publications
Since early 2020, disease caused by the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) has become a global pandemic, causing millions of infections and deaths …
(SARS-CoV-2) has become a global pandemic, causing millions of infections and deaths …
NF-κB-interacting long noncoding RNA regulates HIV-1 replication and latency by repressing NF-κB signaling
H Wang, Y Liu, C Huan, J Yang, Z Li, B Zheng… - Journal of …, 2020 - Am Soc Microbiol
ABSTRACT NF-κB-interacting long noncoding RNA (NKILA) was recently identified as a
negative regulator of NF-κB signaling and plays an important role in the development of …
negative regulator of NF-κB signaling and plays an important role in the development of …
Natural product-derived compounds in HIV suppression, remission, and eradication strategies
While combination antiretroviral therapy (cART) has successfully converted HIV to a chronic
but manageable infection in many parts of the world, HIV continues to persist within latent …
but manageable infection in many parts of the world, HIV continues to persist within latent …
Identification of novel HIV-1 latency-reversing agents from a library of marine natural products
K Richard, DE Williams, ED De Silva, MA Brockman… - Viruses, 2018 - mdpi.com
Natural products originating from marine and plant materials are a rich source of chemical
diversity and unique antimicrobials. Using an established in vitro model of HIV-1 latency, we …
diversity and unique antimicrobials. Using an established in vitro model of HIV-1 latency, we …
Marine-Derived Bioactive Metabolites as a Potential Therapeutic Intervention in Managing Viral Diseases: Insights from the SARS-CoV-2 In Silico and Pre-Clinical …
Worldwide urbanization and subsequent migration have accelerated the emergence and
spread of diverse novel human diseases. Among them, diseases caused by viruses could …
spread of diverse novel human diseases. Among them, diseases caused by viruses could …
The development of the bengamides as new antibiotics against drug-resistant bacteria
C Porras-Alcalá, F Moya-Utrera, M García-Castro… - Marine Drugs, 2022 - mdpi.com
The bengamides comprise an interesting family of natural products isolated from sponges
belonging to the prolific Jaspidae family. Their outstanding antitumor properties, coupled …
belonging to the prolific Jaspidae family. Their outstanding antitumor properties, coupled …
Novel antiretroviral structures from marine organisms
In spite of significant advancements and success in antiretroviral therapies directed against
HIV infection, there is no cure for HIV, which scan persist in a human body in its latent form …
HIV infection, there is no cure for HIV, which scan persist in a human body in its latent form …