Novel drug delivery systems for the management of dry eye

N Nagai, H Otake - Advanced drug delivery reviews, 2022 - Elsevier
Dry eye disease (DED) is a frequently observed eye complaint, which has recently attracted
considerable research interest. Conventional therapy for DED involves the use of artificial …

Nanoencapsulation, nano-guard for pesticides: a new window for safe application

MD Nuruzzaman, MM Rahman, Y Liu… - Journal of agricultural …, 2016 - ACS Publications
The application of nanotechnology in pesticide delivery is relatively new and in the early
stages of development. This technology aims to reduce the indiscriminate use of …

Ocular drug delivery barriers—role of nanocarriers in the treatment of anterior segment ocular diseases

RD Bachu, P Chowdhury, ZHF Al-Saedi, PK Karla… - Pharmaceutics, 2018 - mdpi.com
Ocular drug delivery is challenging due to the presence of anatomical and physiological
barriers. These barriers can affect drug entry into the eye following multiple routes of …

[HTML][HTML] Nanotechnology-based strategies for treatment of ocular disease

Y Weng, J Liu, S Jin, W Guo, X Liang, Z Hu - Acta pharmaceutica sinica B, 2017 - Elsevier
Ocular diseases include various anterior and posterior segment diseases. Due to the unique
anatomy and physiology of the eye, efficient ocular drug delivery is a great challenge to …

Polymeric long-acting drug delivery systems (LADDS) for treatment of chronic diseases: Inserts, patches, wafers, and implants

H Abdelkader, Z Fathalla, A Seyfoddin… - Advanced drug delivery …, 2021 - Elsevier
Non-oral long-acting drug delivery systems (LADDS) encompass a range of technologies for
precisely delivering drug molecules into target tissues either through the systemic circulation …

Accelerating the translation of nanomaterials in biomedicine

S Mitragotri, DG Anderson, X Chen, EK Chow, D Ho… - ACS …, 2015 - ACS Publications
Due to their size and tailorable physicochemical properties, nanomaterials are an emerging
class of structures utilized in biomedical applications. There are now many prominent …

[HTML][HTML] Design principles of ocular drug delivery systems: importance of drug payload, release rate, and material properties

A Subrizi, EM Del Amo, V Korzhikov-Vlakh… - Drug discovery today, 2019 - Elsevier
Highlights•Ocular drug delivery is a field in which regular ADME tools are not useful.•
Pharmacokinetics based dosing aid for ocular drug delivery is presented.•User-friendly …

Niosomal drug delivery systems for ocular disease—Recent advances and future prospects

S Durak, M Esmaeili Rad, A Alp Yetisgin, H Eda Sutova… - Nanomaterials, 2020 - mdpi.com
The eye is a complex organ consisting of several protective barriers and particular defense
mechanisms. Since this organ is exposed to various infections, genetic disorders, and visual …

Drug delivery to the eye: what benefits do nanocarriers offer?

RR Joseph, SS Venkatraman - Nanomedicine, 2017 - Taylor & Francis
Ocular drug delivery has seen several advances in the past few decades, with respect to
new drugs, improved formulations, targeted delivery, as well as exploration of new routes of …

Sustained-release from nanocarriers: a review

JV Natarajan, C Nugraha, XW Ng… - Journal of Controlled …, 2014 - Elsevier
Nanocarriers have been explored for delivering drugs and other bioactive molecules for well
over 35 years. Since the introduction of Doxil®, a nanoliposomal delivery system for the …