Melatonin is an old and ubiquitous molecule in nature showing multiple mechanisms of
action and functions in practically every living organism. In mammals, pineal melatonin …

Alzheimer's disease (AD) is a highly complex neurodegenerative disorder of the aged that
has multiple factors which contribute to its etiology in terms of initiation and progression. This …

The metabolic syndrome (M et S) is a cluster of metabolic abnormalities associated with
increased risk for cardiovascular diseases. Apart from its powerful antioxidant properties, the …

Introduction: Melatonin is a pineal hormone that has acquired several unique modes of
regulating the physiological effects in mammals due to its characteristic phylogenetic history …

Metabolic syndrome (MetS) is characterised by symptoms of obesity, insulin resistance,
hypertension, dyslipidemia and diabetes mellitus. The pathophysiological mechanisms …

The pineal hormone melatonin is known to influence insulin secretion via the G‐protein‐
coupled receptor isoforms MT 1 and MT 2. The present study was aimed to further elucide …

Hibernation is an energy-saving strategy which is widely adopted by heterothermic
mammals to survive in the harsh environment. The greater horseshoe bat (Rhinolophus …

Abstract Melatonin (N-acetyl-5-methoxy-tryptamine) is an effective antioxidant and free
radical scavenger, that has important biological effects in multiple cell types and species …

Bats have an unusually large volume of endocrine tissue, with a large population of beta
cells and an elevated sensitivity to glucose and insulin. This makes them excellent animal …

This article is part of a Special Issue “Energy Balance”. Hibernation allows mammals to
survive in cold climates and during times of reduced food availability. Drastic physiological …