Biochemistry and molecular biology of flaviviruses
Flaviviruses, such as dengue, Japanese encephalitis, tick-borne encephalitis, West Nile,
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
yellow fever, and Zika viruses, are critically important human pathogens that sicken a …
[HTML][HTML] Zika virus: History, epidemiology, transmission, and clinical presentation
BH Song, SI Yun, M Woolley, YM Lee - Journal of neuroimmunology, 2017 - Elsevier
Zika virus (ZIKV), a mosquito-borne positive-stranded RNA virus of the family Flaviviridae
(genus Flavivirus), is now causing an unprecedented large-scale outbreak in the Americas …
(genus Flavivirus), is now causing an unprecedented large-scale outbreak in the Americas …
Receptors and routes of dengue virus entry into the host cells
C Cruz-Oliveira, JM Freire… - FEMS microbiology …, 2015 - academic.oup.com
Dengue is the most prevalent arthropod-borne viral disease, caused by dengue virus, a
member of the Flaviviridae family. Its worldwide incidence is now a major health problem …
member of the Flaviviridae family. Its worldwide incidence is now a major health problem …
[HTML][HTML] Flavivirus receptors: diversity, identity, and cell entry
M Laureti, D Narayanan, J Rodriguez-Andres… - Frontiers in …, 2018 - frontiersin.org
Flaviviruses are emerging and re-emerging arthropod-borne pathogens responsible for
significant mortality and morbidity worldwide. The genus comprises more than seventy …
significant mortality and morbidity worldwide. The genus comprises more than seventy …
Envelope protein ubiquitination drives entry and pathogenesis of Zika virus
Zika virus (ZIKV) belongs to the family Flaviviridae, and is related to other viruses that cause
human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurological …
human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurological …
[HTML][HTML] Nonhuman primate models of human viral infections
JD Estes, SW Wong, JM Brenchley - Nature Reviews Immunology, 2018 - nature.com
Humans have a close phylogenetic relationship with nonhuman primates (NHPs) and share
many physiological parallels, such as highly similar immune systems, with them. Importantly …
many physiological parallels, such as highly similar immune systems, with them. Importantly …
Neutralization of virus infectivity by antibodies: old problems in new perspectives
PJ Klasse - Advances in biology, 2014 - Wiley Online Library
Neutralizing antibodies (NAbs) can be both sufficient and necessary for protection against
viral infections, although they sometimes act in concert with cellular immunity. Successful …
viral infections, although they sometimes act in concert with cellular immunity. Successful …
[HTML][HTML] Serological cross-reactivity among common flaviviruses
The Flavivirus genus is made up of viruses that are either mosquito-borne or tick-borne and
other viruses transmitted by unknown vectors. Flaviviruses present a significant threat to …
other viruses transmitted by unknown vectors. Flaviviruses present a significant threat to …
Vaccine development as a means to control dengue virus pathogenesis: do we know enough?
TC Pierson, MS Diamond - Annual Review of Virology, 2014 - annualreviews.org
Dengue virus (DENV) is a mosquito-transmitted RNA virus responsible for 390 million
infections each year and significant morbidity and mortality throughout tropical and …
infections each year and significant morbidity and mortality throughout tropical and …
[HTML][HTML] Screening bioactives reveals nanchangmycin as a broad spectrum antiviral active against Zika virus
K Rausch, BA Hackett, NL Weinbren, SM Reeder… - Cell reports, 2017 - cell.com
Zika virus is an emerging arthropod-borne flavivirus for which there are no vaccines or
specific therapeutics. We screened a library of 2,000 bioactive compounds for their ability to …
specific therapeutics. We screened a library of 2,000 bioactive compounds for their ability to …