[HTML][HTML] Origin, differentiation, and function of intestinal macrophages
CC Bain, A Schridde - Frontiers in immunology, 2018 - frontiersin.org
Macrophages are increasingly recognized as essential players in the maintenance of
intestinal homeostasis and as key sentinels of the intestinal immune system. However …
intestinal homeostasis and as key sentinels of the intestinal immune system. However …
[HTML][HTML] Regulation of the host immune system by helminth parasites
RM Maizels, HJ McSorley - Journal of Allergy and Clinical Immunology, 2016 - Elsevier
Helminth parasite infections are associated with a battery of immunomodulatory
mechanisms that affect all facets of the host immune response to ensure their persistence …
mechanisms that affect all facets of the host immune response to ensure their persistence …
Exposure to lung-migrating helminth protects against murine SARS-CoV-2 infection through macrophage-dependent T cell activation
OO Oyesola, KL Hilligan, S Namasivayam… - Science …, 2023 - science.org
Helminth endemic regions report lower COVID-19 morbidity and mortality. Here, we show
that lung remodeling from a prior infection with a lung-migrating helminth, Nippostrongylus …
that lung remodeling from a prior infection with a lung-migrating helminth, Nippostrongylus …
Macrophages in bone fracture healing: their essential role in endochondral ossification
C Schlundt, T El Khassawna, A Serra, A Dienelt… - Bone, 2018 - Elsevier
In fracture healing, skeletal and immune system are closely interacting through common cell
precursors and molecular mediators. It is thought that the initial inflammatory reaction, which …
precursors and molecular mediators. It is thought that the initial inflammatory reaction, which …
Macrophages in intestinal homeostasis and inflammation
CC Bain, AMI Mowat - Immunological reviews, 2014 - Wiley Online Library
The intestine contains the largest pool of macrophages in the body which are essential for
maintaining mucosal homeostasis in the face of the microbiota and the constant need for …
maintaining mucosal homeostasis in the face of the microbiota and the constant need for …
[HTML][HTML] Extracellular vesicles from a helminth parasite suppress macrophage activation and constitute an effective vaccine for protective immunity
Recent studies have demonstrated that many parasites release extracellular vesicles (EVs),
yet little is known about the specific interactions of EVs with immune cells or their functions …
yet little is known about the specific interactions of EVs with immune cells or their functions …
[HTML][HTML] Diversity and functions of intestinal mononuclear phagocytes
T Joeris, K Müller-Luda, WW Agace, AMI Mowat - Mucosal immunology, 2017 - Elsevier
The intestinal lamina propria (LP) contains a diverse array of mononuclear phagocyte (MNP)
subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident …
subsets, including conventional dendritic cells (cDC), monocytes and tissue-resident …
Commensal-pathogen interactions in the intestinal tract: lactobacilli promote infection with, and are promoted by, helminth parasites
The intestinal microbiota are pivotal in determining the developmental, metabolic and
immunological status of the mammalian host. However, the intestinal tract may also …
immunological status of the mammalian host. However, the intestinal tract may also …
[HTML][HTML] IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection
VS Pelly, Y Kannan, SM Coomes, LJ Entwistle… - Mucosal …, 2016 - Elsevier
Immunity to many human and murine gastrointestinal helminth parasites requires interleukin-
4 (IL-4)-directed type 2 helper (TH 2) differentiation of CD4+ T cells to elicit type-2 immunity …
4 (IL-4)-directed type 2 helper (TH 2) differentiation of CD4+ T cells to elicit type-2 immunity …
[HTML][HTML] Host protective roles of type 2 immunity: parasite killing and tissue repair, flip sides of the same coin
JE Allen, TE Sutherland - Seminars in immunology, 2014 - Elsevier
Metazoan parasites typically induce a type 2 immune response, characterized by T helper 2
(Th2) cells that produce the cytokines IL-4, IL-5 and IL-13 among others. The type 2 …
(Th2) cells that produce the cytokines IL-4, IL-5 and IL-13 among others. The type 2 …