Nicotinamide adenine dinucleotide (NAD+) and its metabolites function as critical regulators
to maintain physiologic processes, enabling the plastic cells to adapt to environmental …

Nicotinamide phosphoribosyltransferase (NAMPT) is a regulator of the intracellular
nicotinamide adenine dinucleotide (NAD) pool. NAD is an essential coenzyme involved in …

Nicotinamide adenine dinucleotide (NAD) is an important co-factor involved in numerous
physiological processes, including metabolism, post-translational protein modification, and …

Nicotinamide adenine dinucleotide (NAD) is an important coenzyme that participates in
various energy metabolism pathways, including glycolysis, β-oxidation, and oxidative …

This review focuses on the contribution of white, brown, and perivascular adipose tissues to
the pathophysiology of obesity and its associated metabolic and vascular complications …

BACKGROUND Metabolic and endocrine alterations in women with polycystic ovary
syndrome (PCOS) affect adipose tissue mass and distribution. PCOS is characterised by …

Background There is currently an unmet clinical need to develop better pharmacological
treatments to improve glucose handling in Type II Diabetes patients with obesity. To this end …

Obesity is currently one the largest epidemics in the industrialized world. It is also the nexus
on which numerous costly chronic diseases, such as hypertension, hyperlipidemia, T2D …

Polycystic ovary syndrome (PCOS) and endometriosis are frequent diseases of the female
reproductive tract causing high morbidity as they can significantly affect fertility and quality of …

The dysregulation of the β-cell functional mass, which is a reduction in the number of β-cells
and their ability to secure adequate insulin secretion, represents a key mechanistic factor …