Cytokines, inflammation and colon cancer

L Klampfer - Current cancer drug targets, 2011 - ingentaconnect.com
Patients with inflammatory bowel diseases, such as ulcerative colitis and Crohn's disease,
are at increased risk of developing colon cancer, confirming that chronic inflammation …

IL-1 signaling in tumor microenvironment

W Zhang, N Borcherding, R Kolb - … : The Role of Interleukins–Part A, 2020 - Springer
Abstract Interleukin 1 (IL-1) has long been known for its pleiotropic effects on inflammation
that plays a complex, and sometimes contrasting, role in different stages of cancer …

Blocking Dectin-1 prevents colorectal tumorigenesis by suppressing prostaglandin E2 production in myeloid-derived suppressor cells and enhancing IL-22 binding …

C Tang, H Sun, M Kadoki, W Han, X Ye… - Nature …, 2023 - nature.com
Abstract Dectin-1 (gene Clec7a), a receptor for β-glucans, plays important roles in the host
defense against fungi and immune homeostasis of the intestine. Although this molecule is …

Inflammatory parameters in Caco-2 cells: Effect of stimuli nature, concentration, combination and cell differentiation

J Van De Walle, A Hendrickx, B Romier, Y Larondelle… - Toxicology in Vitro, 2010 - Elsevier
Enterocytes regulate gut maintenance and defence by secreting and responding to
inflammatory mediators and by modulating the intestinal epithelial permeability. In order to …

Melatonin reduces inflammatory response in human intestinal epithelial cells stimulated by interleukin‐1β

G Mannino, F Caradonna, I Cruciata… - Journal of pineal …, 2019 - Wiley Online Library
Melatonin is the main secretory product of the pineal gland, and it is involved in the
regulation of periodic events. A melatonin production independent of the photoperiod is …

Immune regulation and inflammation inhibition of Arctium lappa L. polysaccharides by TLR4/NF-κB signaling pathway in cells

F Zeng, Y Li, X Zhang, L Shen, X Zhao, T Beta… - International Journal of …, 2024 - Elsevier
Arctium lappa L. polysaccharides (ALP) are important active ingredients of burdocks with
various bioactivities. In the present study, a crude polysaccharide was extracted from A …

Suppression of COX-2, IL-1β and TNF-α expression and leukocyte infiltration in inflamed skin by bioactive compounds from Rosmarinus officinalis L.

ES Mengoni, G Vichera, LA Rigano… - Fitoterapia, 2011 - Elsevier
In the present study, we evaluated the effects of extracts and purified compounds from fresh
leaves of Rosmarinus officinalis L. Pretreatment with the major anti-inflammatory …

p38/NF‐kB‐dependent expression of COX‐2 during differentiation and inflammatory response of chondrocytes

V Ulivi, P Giannoni, C Gentili… - Journal of cellular …, 2008 - Wiley Online Library
Studying cartilage differentiation, we observed the emergence of inflammation‐related
proteins suggesting that a common pathway was activated in cartilage differentiation and …

[HTML][HTML] Anti-inflammatory effect of low intensity ultrasound (LIUS) on complete Freund's adjuvant-induced arthritis synovium

JI Chung, S Barua, BH Choi, BH Min, HC Han… - Osteoarthritis and …, 2012 - Elsevier
OBJECTIVES: Arthritis with intra-articular inflammation was accompanied by joint pain,
swelling, and stiffness leading to significant functional impairment. Thus, regulation of joint …

Vitamin D, inflammation, and colorectal cancer progression: a review of mechanistic studies and future directions for epidemiological studies

AS van Harten-Gerritsen, MGJ Balvers… - … Biomarkers & Prevention, 2015 - AACR
Survival from colorectal cancer is positively associated with vitamin D status. However,
whether this association is causal remains unclear. Inflammatory processes may link vitamin …