Role of biomarkers for the prevention, assessment, and management of heart failure: a scientific statement from the American Heart Association
SL Chow, AS Maisel, I Anand, B Bozkurt, RA De Boer… - Circulation, 2017 - Am Heart Assoc
Background and Purpose: Natriuretic peptides have led the way as a diagnostic and
prognostic tool for the diagnosis and management of heart failure (HF). More recent …
prognostic tool for the diagnosis and management of heart failure (HF). More recent …
2017 ACC/AHA/HFSA focused update of the 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology/American …
The purpose of this focused update is to update the “2013 ACCF/AHA Guideline for the
Management of Heart Failure” 9 (2013 HF guideline) in areas in which new evidence has …
Management of Heart Failure” 9 (2013 HF guideline) in areas in which new evidence has …
Potential impact and study considerations of metabolomics in cardiovascular health and disease: a scientific statement from the American Heart Association
Through the measure of thousands of small-molecule metabolites in diverse biological
systems, metabolomics now offers the potential for new insights into the factors that …
systems, metabolomics now offers the potential for new insights into the factors that …
[HTML][HTML] Metabolic signatures and risk of type 2 diabetes in a Chinese population: an untargeted metabolomics study using both LC-MS and GC-MS
Aims/hypothesis Metabolomics has provided new insight into diabetes risk assessment. In
this study we characterised the human serum metabolic profiles of participants in the …
this study we characterised the human serum metabolic profiles of participants in the …
New advances in analytical methods for mass spectrometry-based large-scale metabolomics study
X Liu, L Zhou, X Shi, G Xu - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Large-scale metabolomics study based on large population cohorts is increasingly applied
to identify important metabolites or critical metabolic alterations related to the metabolite …
to identify important metabolites or critical metabolic alterations related to the metabolite …
Lipid profiles and heart failure risk: results from two prospective studies
C Wittenbecher, F Eichelmann, E Toledo… - Circulation …, 2021 - Am Heart Assoc
Rationale: Altered lipid metabolism has been implicated in heart failure (HF) development,
but no prospective studies have examined comprehensive lipidomics data and subsequent …
but no prospective studies have examined comprehensive lipidomics data and subsequent …
Branched-chain amino acids as critical switches in health and disease
Zhang et al Branched-Chain Amino Acids 1013 composed of 3 subunits: E1, E2, and E3. 1,
12, 14 The E1 subunit of the BCKD complex (BCKDC) is a tetramer composed of 2 α …
12, 14 The E1 subunit of the BCKD complex (BCKDC) is a tetramer composed of 2 α …
Metabolomic markers of ultra-processed food and incident CKD
Background High ultra-processed food consumption is associated with higher risk of CKD.
However, there is no biomarker for ultra-processed food, and the mechanism through which …
However, there is no biomarker for ultra-processed food, and the mechanism through which …
Metabolomic pattern predicts incident coronary heart disease: findings from the Atherosclerosis Risk in Communities Study
Objective—Alterations in the serum metabolome may be detectable in at-risk individuals
before the onset of coronary heart disease (CHD). Identifying metabolomic signatures …
before the onset of coronary heart disease (CHD). Identifying metabolomic signatures …
Elucidating the role of blood metabolites on pancreatic cancer risk using two‐sample Mendelian randomization analysis
Pancreatic ductal adenocarcinoma (PDAC) is an uncommon but highly fatal malignancy.
Identifying causal metabolite biomarkers offers an opportunity to facilitate effective risk …
Identifying causal metabolite biomarkers offers an opportunity to facilitate effective risk …