Cardiovascular risks associated with gender and aging

JL Rodgers, J Jones, SI Bolleddu… - Journal of …, 2019 - mdpi.com
The aging and elderly population are particularly susceptible to cardiovascular disease. Age
is an independent risk factor for cardiovascular disease (CVD) in adults, but these risks are …

Estrogen receptor signaling mechanisms

N Fuentes, P Silveyra - Advances in protein chemistry and structural …, 2019 - Elsevier
The primary female sex hormones, estrogens, are responsible for the control of functions of
the female reproductive system, as well as the development of secondary sexual …

Role of estrogen receptors in health and disease

P Chen, B Li, L Ou-Yang - Frontiers in endocrinology, 2022 - frontiersin.org
Estrogen receptors (ERs) regulate multiple complex physiological processes in humans.
Abnormal ER signaling may result in various disorders, including reproductive system …

Cardiovascular risk factors and physical activity for the prevention of cardiovascular diseases in the elderly

L Ciumărnean, MV Milaciu, V Negrean… - International Journal of …, 2021 - mdpi.com
Cardiovascular diseases create an important burden on the public health systems,
especially in the elderly, mostly because this group of patients frequently suffer from multiple …

Risk factors of severe COVID-19: a review of host, viral and environmental factors

L Zsichla, V Müller - Viruses, 2023 - mdpi.com
The clinical course and outcome of COVID-19 are highly variable, ranging from
asymptomatic infections to severe disease and death. Understanding the risk factors of …

Protective effects of estrogen on cardiovascular disease mediated by oxidative stress

D Xiang, Y Liu, S Zhou, E Zhou… - Oxidative medicine and …, 2021 - Wiley Online Library
Perimenopause is an important stage of female senescence. Epidemiological investigation
has shown that the incidence of cardiovascular disease in premenopausal women is lower …

Sex differences in mechanisms of arterial stiffness

JJ DuPont, RM Kenney, AR Patel… - British journal of …, 2019 - Wiley Online Library
Arterial stiffness progressively increases with aging and is an independent predictor of
cardiovascular disease (CVD) risk. Evidence supports that there are sex differences in the …

The role of estrogen receptors in cardiovascular disease

L Aryan, D Younessi, M Zargari, S Banerjee… - International journal of …, 2020 - mdpi.com
Cardiovascular Diseases (CVDs) are the leading cause of death globally. More than 17
million people die worldwide from CVD per year. There is considerable evidence suggesting …

[HTML][HTML] Sex differences in frailty: comparisons between humans and preclinical models

AE Kane, SE Howlett - Mechanisms of Ageing and Development, 2021 - Elsevier
Frailty can be viewed as a state of physiological decline that increases susceptibility to
adverse health outcomes. This loss of physiological reserve means that even small stressors …

Role of diet and exercise in aging, Alzheimer's disease, and other chronic diseases

S Khemka, A Reddy, RI Garcia, M Jacobs… - Ageing Research …, 2023 - Elsevier
Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterized by
memory loss and multiple cognitive impairments. Genetic mutations cause a small …