Planar polarity describes the coordinated polarisation of cells or structures in the plane of a
tissue. The patterning mechanisms that underlie planar polarity are well characterised in …

Planar cell polarity (PCP) refers to the coordinated alignment of cell polarity across the
tissue plane. Key to the establishment of PCP is asymmetric partitioning of cortical PCP …

Planar cell polarization entails establishment of cellular asymmetries within the tissue plane.
An evolutionarily conserved planar cell polarity (PCP) signaling system employs intra-and …

Cilia are important cellular structures that have been implicated in a variety of signaling
cascades. In this review, we discuss the current evidence for and against a link between cilia …

In addition to activating β-catenin/TCF transcriptional complexes, Wnt proteins can elicit a
variety of other responses. These are often lumped together under the denominator …

Vestibular epithelia of the inner ear detect head motions over a wide range of amplitudes
and frequencies. In mammals, afferent nerve fibers from central and peripheral zones of …

Dishevelled (Dvl) proteins are important signaling components of both the canonical β-
catenin/Wnt pathway, which controls cell proliferation and patterning, and the planar cell …

Planar cell polarity (PCP) is critical for morphogenesis in metazoans. PCP in vertebrates
regulates stereocilia alignment in neurosensory cells of the cochlea and closure of the …

Planar cell polarity (PCP), the orientation and alignment of cells within a sheet, is a
ubiquitous cellular property that is commonly governed by the conserved set of proteins …

Planar cell polarity (PCP) refers to coordinated polarization of cells within the plane of a cell
sheet. A conserved signaling pathway is required for the establishment of PCP in epithelial …