Okadaic acid: more than a diarrheic toxin

V Valdiglesias, MV Prego-Faraldo, E Pásaro, J Méndez… - Marine Drugs, 2013 - mdpi.com
Okadaic acid (OA) is one of the most frequent and worldwide distributed marine toxins. It is
easily accumulated by shellfish, mainly bivalve mollusks and fish, and, subsequently, can be …

Dinoflagellate polyether within the yessotoxin, pectenotoxin and okadaic acid toxin groups: Characterization, analysis and human health implications

HJ Dominguez, B Paz, AH Daranas, M Norte… - Toxicon, 2010 - Elsevier
Diarrhetic Shellfish Poisoning (DSP) is a specific type of food poisoning, characterized by
severe gastrointestinal illness due to the ingestion of filter feeding bivalves contaminated …

Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells

S Kumar, CG Yedjou, PB Tchounwou - Journal of experimental & clinical …, 2014 - Springer
Background Acute promyelocytic leukemia (APL) is a subtype of acute myeloid leukemia
(AML), which accounts for approximately 10% of all acute myloid leukemia cases. It is a …

[HTML][HTML] Cytotoxicity and intestinal permeability of phycotoxins assessed by the human Caco-2 cell model

J Qiu, J Zhang, A Li - Ecotoxicology and Environmental Safety, 2023 - Elsevier
Phycotoxins are a class of multiple natural metabolites produced by microalgae in marine
and freshwater ecosystems that bioaccumulate in food webs, particularly in shellfish, having …

Development of mussel mRNA profiling: can gene expression trends reveal coastal water pollution?

P Venier, C De Pittà, A Pallavicini, F Marsano… - Mutation Research …, 2006 - Elsevier
Marine bivalves of the genus Mytilus are intertidal filter-feeders commonly used as
biosensors of coastal pollution. Mussels adjust their functions to ordinary environmental …

Duplexed aptamer-isothermal amplification-based nucleic acid-templated copper nanoparticles for fluorescent detection of okadaic acid

W Shan, J Sun, R Liu, W Xu, B Shao - Sensors and Actuators B: Chemical, 2022 - Elsevier
Okadaic acid (OA) is a major marine toxin that can cause diarrheic shellfish poisoning
(DSP). Because of food safety concerns, simple and reliable field assays are in high …

Fluorescence in situ hybridization in combination with the comet assay and micronucleus test in genetic toxicology

GG Hovhannisyan - Molecular cytogenetics, 2010 - Springer
Comet assay and micronucleus (MN) test are widely applied in genotoxicity testing and
biomonitoring. While comet assay permits to measure direct DNA-strand breaking capacity …

In vivo genotoxicity testing of the amnesic shellfish poison (domoic acid) in piscine erythrocytes using the micronucleus test and the comet assay

T Çavaş, S Könen - Aquatic Toxicology, 2008 - Elsevier
Domoic acid (DA) is a neurotoxic amino acid naturally produced in the marine environment
by some diatom species belonging to the genus Pseudo-nitzschia. Although the neurotoxic …

Assessment of Cr (VI)-induced cytotoxicity and genotoxicity using high content analysis

CM Thompson, Y Fedorov, DD Brown, M Suh… - 2012 - journals.plos.org
Oral exposure to high concentrations of hexavalent chromium [Cr (VI)] induces intestinal
redox changes, villus cytotoxicity, crypt hyperplasia, and intestinal tumors in mice. To assess …

Phycotoxin-enriched sea spray aerosols: methods, mechanisms, and human exposure

E Van Acker, S Huysman, M De Rijcke… - … science & technology, 2021 - ACS Publications
To date, few studies have examined the role of sea spray aerosols (SSAs) in human
exposure to harmful and beneficial marine compounds. Two groups of phycotoxins …