More frequent and intense periods of extreme heat (heatwaves) represent the most direct
challenge to human health posed by climate change. Older adults are particularly …

Epidemiological and biological plausibility studies support a cause-and-effect relationship
between increased levels of physical activity or cardiorespiratory fitness and reduced …

Echocardiographic assessment of left ventricular (LV) diastolic function is an integral part of
the routine evaluation of patients presenting with symptoms of dyspnea or heart failure. The …

Background Low physical activity has been shown to be one of the most common
components of frailty, and interventions have been considered to prevent or reverse this …

Substantial evidence has established the value of high levels of physical activity, exercise
training (ET), and overall cardiorespiratory fitness in the prevention and treatment of …

This review focuses on how blood flow to contracting skeletal muscles is regulated during
exercise in humans. The idea is that blood flow to the contracting muscles links oxygen in …

Chronic diseases are major killers in the modern era. Physical inactivity is a primary cause
of most chronic diseases. The initial third of the article considers: activity and prevention …

Approximately half of all patients with heart failure have preserved ejection fraction (HFpEF)
and, as life expectancies continue to increase in western societies, the prevalence of HFpEF …

Cardiovascular diseases are the most prominent maladies in aging societies. Indeed, aging
promotes the structural and functional declines of both the heart and the blood circulation …

Although the observed progress in the cardiovascular disease treatment, the incidence of
new and recurrent coronary artery disease remains elevated and constitutes the leading …