Background Inotropes and vasopressors are frequently administered to critically ill patients
in order to improve haemodynamic function and restore adequate organ perfusion …

In cardiac surgery, postoperative low cardiac output has been shown to correlate with
increased rates of organ failure and mortality. Catecholamines have been the standard …

Background Inodilators are commonly used in critically ill patients, but their effect on survival
has not been properly studied to date. The objective of this work was to conduct a network …

Background There has been conflicting evidence concerning the effect of levosimendan on
clinical outcomes in patients undergoing cardiac surgery. Therefore, we performed a …

Background The impact of levosimendan treatment on clinical outcome in patients
undergoing extracorporeal membrane oxygenation (ECMO) support after cardiovascular …

Background Several studies suggested beneficial effects of perioperative levosimendan on
postoperative outcome after cardiac surgery. However, three large randomized controlled …

Myocardial contractility and relaxation are highly dependent on calcium homeostasis.
Immature myocardium, as in pediatric patients, is thought to be more dependent on …

Severe postoperative complications can affect cardiac surgery patients. Levosimendan is a
novel calcium sensitizer commonly administered after cardiac surgery. However, the patient …

It is currently unknown whether levosimendan can improve clinical outcomes in patients
undergoing cardiac surgery. This meta-analysis aimed to assess the effect of levosimendan …

Background The objective was to evaluate the effect of epinephrine and levosimendan on
the left ventricle myocardial performance index in patients undergoing on-pump coronary …