Sulfonyl fluorides as targets and substrates in the development of new synthetic methods

TSB Lou, MC Willis - Nature Reviews Chemistry, 2022 - nature.com
The advent of sulfur (vi)-fluoride exchange (SuFEx) processes as transformations with click-
like reactivity has invigorated research into electrophilic species featuring a sulfur–fluorine …

Recent development of aryl diazonium chemistry for the derivatization of aromatic compounds

F Mo, D Qiu, L Zhang, J Wang - Chemical Reviews, 2021 - ACS Publications
Aryl diazonium salts are versatile building blocks in organic synthesis. In light of the ever-
increasing importance of aryl diazonium salts spanning most disciplines of the chemical …

The growing applications of SuFEx click chemistry

AS Barrow, CJ Smedley, Q Zheng, S Li… - Chemical Society …, 2019 - pubs.rsc.org
SuFEx (Sulfur Fluoride Exchange) is a modular, next generation family of click reactions,
geared towards the rapid and reliable assembly of functional molecules. This review …

Radical Hydro‐Fluorosulfonylation of Unactivated Alkenes and Alkynes

P Wang, H Zhang, M Zhao, S Ji, L Lin… - Angewandte Chemie …, 2022 - Wiley Online Library
Recently, radical fluorosulfonylation is emerging as an appealing approach for the synthesis
of sulfonyl fluorides, which are highly in demand in various disciplines, particularly in …

The emerging applications of sulfur (VI) fluorides in catalysis

C Lee, AJ Cook, JE Elisabeth, NC Friede… - ACS …, 2021 - ACS Publications
The past decade has witnessed remarkable growth of catalytic transformations in organic
sulfur (VI) fluoride chemistry. This Perspective concentrates exclusively on foundational …

A practical fluorosulfonylating platform via photocatalytic imidazolium-based SO2F radical reagent

W Zhang, H Li, X Li, Z Zou, M Huang, J Liu… - Nature …, 2022 - nature.com
Sulfonyl fluorides are key components in the fields of chemical biology, materials science
and drug discovery. In this line, the highly active SO2F radical has been employed for the …

Chemical and biology of sulfur fluoride exchange (SuFEx) click chemistry for drug discovery

SW Lucas, RZ Qin, KP Rakesh, KSS Kumar, HL Qin - Bioorganic Chemistry, 2023 - Elsevier
Compounds containing an Ssingle bondF bond have garnered intense interest in the
chemical and biological literature. In particular, sulfonyl fluorides (RSO 2 F) are commonly …

Photoredox catalytic radical fluorosulfonylation of olefins enabled by a bench-stable redox-active fluorosulfonyl radical precursor

P Wang, H Zhang, X Nie, T Xu, S Liao - Nature Communications, 2022 - nature.com
Sulfonyl fluorides have attracted considerable and growing research interests from various
disciplines, which raises a high demand for novel and effective methods to access this class …

Electrochemical Oxo‐Fluorosulfonylation of Alkynes under Air: Facile Access to β‐Keto Sulfonyl Fluorides

D Chen, X Nie, Q Feng, Y Zhang… - Angewandte Chemie …, 2021 - Wiley Online Library
Radical fluorosulfonylation is emerging as an appealing approach for the synthesis of
sulfonyl fluorides, which have widespread applications in many fields, in particular in the …

SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase

Q Zheng, JL Woehl, S Kitamura… - Proceedings of the …, 2019 - National Acad Sciences
Sulfur fluoride exchange (SuFEx) has emerged as the new generation of click chemistry. We
report here a SuFEx-enabled, agnostic approach for the discovery and optimization of …