Metabolomics in the context of plant natural products research: From sample preparation to metabolite analysis

MA Salem, L Perez de Souza, A Serag, AR Fernie… - Metabolites, 2020 - mdpi.com
Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …

Cerebrospinal fluid metabolomics: Detection of neuroinflammation in human central nervous system disease

J Yan, U Kuzhiumparambil… - Clinical & …, 2021 - Wiley Online Library
The high morbidity and mortality of neuroinflammatory diseases drives significant interest in
understanding the underlying mechanisms involved in the innate and adaptive immune …

[HTML][HTML] Metabolomics and chemometrics: The next-generation analytical toolkit for the evaluation of food quality and authenticity

P Garcia-Perez, PP Becchi, L Zhang… - Trends in Food Science …, 2024 - Elsevier
Background The advances in NMR and mass spectrometry metabolomics allows a
comprehensive profiling of foods, potentially covering geographical origin, authenticity …

Emerging role of metabolomics in ovarian cancer diagnosis

A Saorin, E Di Gregorio, G Miolo, A Steffan, G Corona - Metabolites, 2020 - mdpi.com
Ovarian cancer is considered a silent killer due to the lack of clear symptoms and efficient
diagnostic tools that often lead to late diagnoses. Over recent years, the impelling need for …

The application of chemometrics in metabolomic and lipidomic analysis data presentation for halal authentication of meat products

V Maritha, PW Harlina, I Musfiroh, AM Gazzali… - Molecules, 2022 - mdpi.com
The halal status of meat products is an important factor being considered by many parties,
especially Muslims. Analytical methods that have good specificity for the authentication of …

Beyond Δ9-tetrahydrocannabinol and cannabidiol: Chemical differentiation of cannabis varieties applying targeted and untargeted analysis

MC Monti, P Frei, S Weber, E Scheurer… - Analytical and …, 2022 - Springer
Cannabis sativa (C. sativa) is commonly chemically classified based on its Δ9-
tetrahydrocannabinol (THC) and cannabidiol (CBD) content ratios. However, the plant …

The integration of Metabolomics with other Omics: insights into understanding prostate Cancer

EP Resurreccion, K Fong - Metabolites, 2022 - mdpi.com
Our understanding of prostate cancer (PCa) has shifted from solely caused by a few genetic
aberrations to a combination of complex biochemical dysregulations with the prostate …

Can plant hormonomics be built on simple analysis? A review

O Vrobel, P Tarkowski - Plant Methods, 2023 - Springer
The field of plant hormonomics focuses on the qualitative and quantitative analysis of the
hormone complement in plant samples, akin to other omics sciences. Plant hormones …

Dysregulation of amino acids and lipids metabolism in schizophrenia with violence

X Chen, J Xu, J Tang, X Dai, H Huang, R Cao, J Hu - BMC psychiatry, 2020 - Springer
Background Many studies have related biochemical characteristics to violence and have
reported schizophrenia could elevated the risk of violent behaviour. However, the metabolic …

[HTML][HTML] Metabolomic studies of anthocyanins in fruits by means of a liquid chromatography coupled to mass spectrometry workflow

JP da Silva Oliveira, RT de Oliveira, AL Guedes… - Current Plant …, 2022 - Elsevier
Among plant pigments, anthocyanins are one of the most important. However, there are
great difficulties related to applying appropriate techniques able to identify molecules with …