Doxorubicin (DOX) constitutes the major constituent of anti-cancer treatment regimens
currently in clinical use. However, the precise mechanisms of DOX's action are not fully …

Supramolecular assemblies are essential components of living organisms. Cellular
scaffolds, such as the cytoskeleton or the cell membrane, are formed via secondary …

Death is the inevitable fate of all living organisms, whether at the individual or cellular level.
For a long time, cell death was believed to be an undesirable but unavoidable final outcome …

Epithelial-mesenchymal transition (EMT) and Cancer stem-like cells (CSCs) are major
factors contributing to the metastasis of cancer cells. Consequently, the signaling pathways …

Autophagy, as a type II programmed cell death, plays crucial roles with autophagy-related
(ATG) proteins in cancer. Up to now, the dual role of autophagy both in cancer progression …

Emerging as a potent anticancer treatment, subcellular targeted cancer therapy has drawn
increasing attention, bringing great opportunities for clinical application. Here, two targeting …

Cell death was once believed to be the result of one of two distinct processes, apoptosis
(also known as programmed cell death) or necrosis (uncontrolled cell death); in recent …

Malignant transformation is characterized by dysregulation of diverse cellular processes that
have been the subject of detailed genetic, biochemical, and structural studies, but only …

With the wide application of plastics in daily life, nanoplastics (NPs) are ubiquitous in
freshwater environments. However, to date, few studies have focused on the mechanism …

Resveratrol is a polyphenolic nutraceutical that exhibits pleiotropic activities in human
subjects. The efficacy, safety, and pharmacokinetics of resveratrol have been documented in …