Self-microemulsifying drug delivery system (SMEDDS) has emerged as a distinctive
approach for the improvement of low bioavailability, high intra-and inter-subject …

The improvement of oral bioavailability of poorly water soluble drug can be considered as
one of the greatest challenges in drug formulation. In recent years today, up to 90% of all …

Objective: The objective of the current research is systematic optimization and development
of microemulsion preconcentrates to get better solubility that results in improvement of oral …

Background and Objective: In the present investigation, we have developed, optimized and
evaluated a self-micro emulsifying drug delivery system (SMEDDS) of an anti-hypertensive …

In modern drug discovery techniques, about 40% of active moieties exhibit poorly water
soluble which and present a major challenge to modern drug delivery system results in low …

Self microemulsifying drug delivery systems (SMEDDS) are defined as isotropic mixtures of
natural or synthetic oils, surfactants and co-solvents/co-surfactants. Upon mild agitation …

Atorvastatin Calcium used to lower cholesterol level in plasma of body by competitive
inhibiting HMG-CoA reductase, the rate determining enzyme in cholesterol biosynthesis via …

Background: Olmesartan medoxomil is an angiotensin II receptor blocker antihypertensive
drug, which has low oral bioavailability because of poor aqueous solubility. Objective: The …

Self-Micro-Emulsifying drug delivery system is the latest and innovative approaches have
been interested in signi icant interest like an effective means for improving solubility …

Quetiapine fumarate is an antipsychotic drug with plasma half-life 6 hr. and having poor oral
bioavailability (9%) because of first pass metabolism. The aim of the present study was to …