The use of engineered ketoreductases (KREDS), both as whole microbial cells and isolated
enzymes, in the highly enantiospecific reduction of prochiral ketones is reviewed. The …

Vitamin B5, also called D-pantothenic acid (D-PA), is a necessary micronutrient that plays an
essential role in maintaining the physiological function of an organism. It is widely used in …

Nitriles are of significant interest in the flavor and fragrance industries with potential
application in cosmetics due to their higher stability than analogous aldehydes. However …

Microbial production of D-pantothenic acid from renewable carbon sources has attracted
significant attention in recent years. Cofactor NADPH is involved in a variety of synthetic …

D-Pantothenic acid (D-PaA) is an essential vitamin for human beings, and the global market
value of calcium pantothenate, the commercial form of D-PaA, has been estimated to be …

Abstract d-(+)-pantothenic acid (DPA) has been widely used in feed and food additives and
pharmaceutical industries. d-(−)-pantolactone (D PL) is a key intermediate in the production …

β-Turn tetrapeptides were demonstrated to catalyze asymmetric aldol reaction of α-branched
aldehydes and α-carbonyl aldehydes, ie glyoxylates and α-ketoaldehydes, to biomimetically …

Abstract d-(−)-Pantolactone (DPL) is a key intermediate for the production of d-(+)-
pantothenate (vitamin B5). Deracemization of d, l-pantolactone (D, L-PL) through oxidizing l …

Biosynthesis of D-pantothenate has been widely studied as D-pantothenate is one kind of
important vitamins used in food and pharmaceuticals. However, the engineered strain for D …

Abstract D-pantolactone (D-PL) is one of the important chiral intermediates in the synthesis
of D-pantothenic acid. Our previous study has revealed that ketopantolactone (KPL) …