[HTML][HTML] Medication-related osteonecrosis of the jaw: definition and best practice for prevention, diagnosis, and treatment

O Nicolatou-Galitis, M Schiødt, RA Mendes… - Oral surgery, oral …, 2019 - Elsevier
Skeletal complications caused by osteoporosis or bone metastases are associated with
considerable pain, increased mortality, and reduced quality of life. Furthermore, such events …

Osteonecrosis of the jaw and antiresorptive agents in benign and malignant diseases: a critical review organized by the ECTS

AD Anastasilakis, J Pepe, N Napoli… - The Journal of …, 2022 - academic.oup.com
Context Antiresorptive therapy significantly reduces fracture risk in patients with benign bone
disease and skeletal-related events (SREs) in patients with bone metastases (BM) …

Infection as an important factor in medication-related osteonecrosis of the jaw (MRONJ)

S Otto, S Aljohani, R Fliefel, S Ecke, O Ristow, E Burian… - Medicina, 2021 - mdpi.com
Medication-related osteonecrosis of the jaw (MRONJ) has become a well-known side effect
of antiresorptive, and antiangiogenic drugs commonly used in cancer management. Despite …

Antiresorptive agent-related osteonecrosis of the jaw (ARONJ): a twist of fate in the bone

T Shibahara - The Tohoku journal of experimental medicine, 2019 - jstage.jst.go.jp
Bisphosphonates (BPs) have been used as antiresorptive agents to treat patients with
osteoporosis or metastatic bone cancer, each of which is characterized by bone loss due to …

[HTML][HTML] Risk of medication-related osteonecrosis of the jaw after dental extractions in patients receiving antiresorptive agents—A retrospective study of 240 patients

R Coropciuc, R Coopman, M Garip, E Gielen, C Politis… - Bone, 2023 - Elsevier
This study investigated the incidence, risk factors, and outcome of medication-related
osteonecrosis of the jaw after dental extractions in patients receiving antiresorptive agents …

Medication-related osteonecrosis of the jaw after tooth extraction in cancer patients: a multicenter retrospective study

T Hasegawa, S Hayashida, E Kondo, Y Takeda… - Osteoporosis …, 2019 - Springer
Root amputation, immunosuppressive therapy, mandibular tooth extraction, pre-existing
inflammation, and longer duration of treatment with bone-modifying agents were significantly …

Prevalence, incidence rate, and risk factors of medication-related osteonecrosis of the jaw in patients with osteoporosis and cancer: a nationwide population-based …

M Ishimaru, S Ono, K Morita, H Matsui… - Journal of Oral and …, 2022 - Elsevier
Purpose Medication-related osteonecrosis of the jaw (MRONJ) is a rare but severe adverse
event of antiresorptive agents. However, the precise prevalence and factors associated with …

Low-level laser therapy prevents medication-related osteonecrosis of the jaw-like lesions via IL-1RA-mediated primary gingival wound healing

Y Zheng, X Dong, S Chen, Y He, J An, M Liu, L He… - BMC Oral Health, 2023 - Springer
Background Medication-related osteonecrosis of the jaw (MRONJ) is a serious debilitating
disease caused by anti-resorption and anti-angiogenesis drugs, significantly affecting …

Long-term oral bisphosphonates delay healing after tooth extraction: a single institutional prospective study

A Shudo, H Kishimoto, K Takaoka, K Noguchi - Osteoporosis International, 2018 - Springer
Tooth extraction in patients receiving bisphosphonates is thought to be a risk factor for
osteonecrosis of the jaw (ONJ); however, ONJ did not develop, even when tooth extraction …

[HTML][HTML] Bisphosphonates and osteonecrosis of the jaws: Clinical and forensic aspects

D Nogueira, IM Caldas, RJ Dinis-Oliveira - Archives of Oral Biology, 2023 - Elsevier
Objective This manuscript aims to provide a comprehensive review of the current knowledge
in the pathophysiology, diagnosis, prevention, and other relevant forensic and clinical …