Increasing evidences suggest that inflammation plays a key role in the pathogenesis of
stroke, a devastating disease second only to cardiac ischemia as a cause of death …

Stroke remains the number one cause of morbidity in the United States. Within weeks to
months after an ischemic event, there is a resolution of inflammation and evidence of …

Background Cerebral ischemia–reperfusion (I/R) injury is a major cause of early
complications and unfavorable outcomes after endovascular thrombectomy (EVT) therapy in …

Ischemic stroke is an acute and serious cerebral vascular disease, which greatly affects
people's health and brings huge economic burden to society. Microglia, as important innate …

Stroke is a lethal cerebral disease with severe sequelae and high mortality. Microglia, the
main immune cell in the cerebrum, possess therapeutic potential for strokes as its specific …

Abstract Aim Ischemia/reperfusion (I/R) injury is the major cause of neurological deficit
following stroke. Our previous study showed neuroprotective effects of hispidulin against …

Objective Huangqin decoction (HQD), a classical traditional Chinese medicinal formula, has
been commonly used to treat gastrointestinal diseases for thousands of years. We …

Objective and design Microglia stimulated by oxygen glucose deprivation (OGD) were
treated with quercetin to investigate the effect on oxidative stress and the inflammatory …

The endocannabinoid system (ECS) comprises two cognate endocannabinoid receptors
referred to as CB1R and CB2R. ECS dysregulation is apparent in neurodegenerative/neuro …

The supply of oxygen and nutrients to the brain is vital for its function and requires a complex
vascular network that, when disturbed, results in profound neurological dysfunction. As part …