Polymorphonuclear neutrophil granulocytes (PMNs) possess numerous effector
mechanisms to kill ingested pathogens as the first line of defence. However, several …

COVID-19 can result in severe lung injury. It remained to be determined why diabetic
individuals with uncontrolled glucose levels are more prone to develop the severe form of …

Histoplasmosis is a systemic mycosis caused by the thermally dimorphic fungus
Histoplasma capsulatum. Although healthy individuals can develop histoplasmosis, the …

Although Candida glabrata is an important human pathogenic yeast, its pathogenicity
mechanisms are largely unknown. Immune evasion strategies seem to play key roles during …

Pathogenic yeasts, either from the environment or the normal flora, have to face phagocytic
cells that constitute the first line of defence during infection. In order to evade or counteract …

Polymorphonuclear neutrophil granulocytes (PMN) are primary antimicrobial effector cells of
the innate immune system and serve to destroy invading pathogens. Although most ingested …

Neutrophils are the most abundant leukocyte in humans and they are among the first white
cells recruited to infected tissues. These leukocytes are essential for the innate immune …

The human immune system uses an arsenal of effector mechanisms to prevent and
counteract infections. Yet, some fungal species are extremely successful as human …

Systemic and endemic mycoses are considered life-threatening respiratory diseases which
are caused by a group of dimorphic fungal pathogens belonging to the genera Histoplasma …

Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …