Ankylosing spondylitis (AS) is an inflammatory autoimmune disease. AS is a prototype form
of spondyloarthropathies (SpA). The precise etiology of AS has not been fully understood …

Ankylosing Spondylitis (AS) is a debilitating rheumatic disease that gives young adults a
severe form of arthritis with pain and stiffness in the axial skeleton. After the discovery of …

The activating natural killer (NK)-cell receptor KIR3DS1 has been linked to the outcome of
various human diseases, including delayed progression of disease caused by human …

Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown etiology, though it
is considered an autoimmune disease. HLA‐B27 is the risk factor most often associated with …

The term spondyloarthritis (SpA) encompasses a group of chronic inflammatory diseases
with common features in terms of clinical presentation and genetic predisposition. SpA is …

Natural killer (NK) cells are important players in the immune defense against viral infections.
The contribution of activating killer immunoglobulin-like receptors (KIRs) and CD94/NKG2C …

Natural killer (NK) cells are large, granular lymphocytes devoted to the defense against
microbial agents and cancer cells, traditionally recognized as an important arm of the innate …

The discovery of the association of HLA B27 with spondyloarthropathy led to more questions
than answers about the role of this gene in disease susceptibility. The realization that HLA …

Objectives. We conducted a case–control study to determine the association between
KIR2D and KIR3D gene polymorphisms and their interaction with HLA alleles in PsA …

This article summarizes the proceedings of a one-day international workshop held in July
2009 on the role of HLA-B27 in the pathogenesis of ankylosing spondylitis (AS) and related …