Simple Summary For tumors to initiate and sustain rapid growth, they need to alter their
metabolic reprograming to support this growth. While many oncogenes upregulate …

Bovine lactoferrin (bLF) presents in milk and has been shown to inhibit several viral
infections. Effective drugs are unavailable for the treatment of dengue virus (DENV) …

Nicotinic acetylcholine receptors containing α9 subunits (α9*-nAChRs) are potential
druggable targets arousing great interest for pain treatment alternative to opioids …

Importance New drugs which provide benefit alongside statin mono-therapy are warranted
to reduce risk of cardiovascular disease. Objective To systematically evaluate the genetically …

Protein degradation is a universal process performed by human cells to recycle unused
proteins and to adapt to an ever-changing environment. Targeted protein degradation (TPD) …

For the past 30 years, the standard of care for epithelial ovarian cancer has essentially
remained unchanged with little progress in the development of novel innovative treatments …

This chapter discusses the enzyme kinetics by means of the Michaelis–Menten kinetics that
goes back to a publication by the German biochemist Leonor Michaelis and Canadian …

Pharmaceutical Biocatalysis; Chemoenzymatic Synthesis of Active Pharmaceutical Ingredients;
Edition 1 Page 1 3KDUPDFHXWLFDO %LRFDWDO\VLV Jenny Stanford Series on Biocatalysis …

A factorial Mendelian randomization study to systematically prioritize genetic targets for the
treatment of cardiovascular disea Page 1 1 A factorial Mendelian randomization study to …

Strong evidence that statin medication is linked to type II diabetes raises questions about the
role of cholesterol in insulin secretion and pancreatic β-cell function. Experimentally induced …