More than 1 out of 10 women worldwide are diagnosed with polycystic ovary syndrome
(PCOS), the leading cause of female reproductive and metabolic dysfunction. Despite its …

It is well understood that sex differences exist between females and males even before they
are born. These sex-dependent differences may contribute to altered growth and …

Accumulating evidence suggests that insults occurring during the perinatal period alter the
developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes …

Developmental origins of adult disease (DoHAD) refers to critical gestational ages during
human fetal development and beyond when the endocrine-metabolic status of the mother …

Adequate maternal vascular adaptations and blood supply to the uterus and placenta are
crucial for optimal oxygen and nutrient transport to growing fetuses of eutherian mammals …

Polycystic ovary syndrome (PCOS) is a multifactorial disorder that arises from interactions
between genetic, environmental and intra-uterine factors. Small-for-gestational-age (SGA) …

Androgen excess (hyperandrogenism) is a common endocrine disorder affecting women of
reproductive age. The potential causes of androgen excess in women include polycystic …

Context Polycystic ovary syndrome (PCOS) is the most common endocrinopathy of
reproductive-aged women. In pregnancy, women with PCOS experience increased risk of …

Elevated maternal testosterone levels are shown to cause fetal growth restriction, eventually
culminating in sex-specific adult-onset hypertension that is more pronounced in males than …

Exposure to bisphenolic chemicals during pregnancy occurs in> 90% of pregnancies.
Bisphenolic compounds can cross the placental barrier reaching fetal circulation. However …