Amifostine protective effect on cisplatin‐treated rat testis

LC Lirdi, T Stumpp, E Sasso‐Cerri… - … Record: Advances in …, 2008 - Wiley Online Library
Cisplatin is a potent drug used in clinical oncology but causes spermatogenesis damage.
Amifostine is a drug used against toxicity caused by ionizing irradiation and …

Insights into antioxidant strategies to counteract radiation-induced male infertility

MA Spadella, EJR Silva, AB Chies… - Antioxidants & Redox …, 2024 - liebertpub.com
Significance: Radiotherapy, which employs ionizing radiation to destroy or prevent the
multiplication of tumor cells, has been increasingly used in the treatment of neoplastic …

Amifostine–doxorubicin association causes long-term prepubertal spermatogonia DNA damage and early developmental arrest

V Vendramini, B Robaire, SM Miraglia - Human Reproduction, 2012 - academic.oup.com
BACKGROUND In a previous study, we found that amifostine provides some protection to
the seminiferous epithelium of prepubertal doxorubicin-treated male rats but does not …

Prunus armeniaca L (apricot) protects rat testes from detrimental effects of low-dose x-rays

MY Ugras, M Kurus, B Ates, H Soylemez, A Otlu… - Nutrition research, 2010 - Elsevier
Exposure to low x-ray doses damages the spermatozoa, mainly by late-onset (ie, after 3
months) oxidative stress. Antioxidants ameliorate oxidation and prevent tissue damage …

[HTML][HTML] The therapeutic potential of amifostine on cyclophosphamide-induced testicular dysfunction in rats: An experimental study

C Kaya, AB Baseskioglu, S Yigitaslan… - International journal …, 2019 - ncbi.nlm.nih.gov
Background Cyclophosphamide (CP) is a well-known alkylating anticancer agent used in
the treatment of various malignant and non-malignant tumors. CP may also cause a variety …

Histopathological and biochemical comparisons of the protective effects of amifostine and l‐carnitine against radiation‐induced acute testicular toxicity in rats

T Aktoz, M Caloglu, V Yurut‐Caloglu, O Yalcin… - Andrologia, 2017 - Wiley Online Library
The aim of this study was to compare the radioprotective efficacies of amifostine (AMI) and l‐
carnitine (LC) against radiation‐induced acute testicular damage. Thirty Wistar albino rats …

The role of amifostine in preventing radiotherapy induced testicular tissue damage in rats

A Gezer, E Karadag-Sari - Biotechnic & Histochemistry, 2022 - Taylor & Francis
The germinal epithelium of the adult testis is susceptible to radiation induced damage.
Amifostine is a drug used to prevent the side effects of radiotherapy (RT) and chemotherapy …

[PDF][PDF] Radioprotective potential of Grewia asiatica fruit extract in mice testis

KV Sharma, R Sisodia - Pharmacologyonline, 2010 - pharmacologyonline.silae.it
The radioprotective effect of Grewia asiatica fruit (GAE) was studied. Method: For study
Swiss albino mice were divided into five groups-1. Control (vehicle treated) 2. GAE treated …

[HTML][HTML] Radioprotective effects of heat-killed mycobacterium tuberculosis in cultured cells and radiosensitive tissues

Y Chen, Y Xu, J Du, J Guo, X Lei, J Cui, C Liu… - Cellular Physiology and …, 2016 - karger.com
Background: Exposure to ionizing radiation (IR) often causes severe damage to
radiosensitive tissues, which limits the use of radiotherapy in cancer patients. Novel safe …

Sertoli cell morphological alterations in albino rats treated with etoposide during prepubertal phase

T Stumpp, E Freymuller… - Microscopy and …, 2008 - academic.oup.com
Sertoli cells are very important to spermatogenesis homeostasis because they control germ
cell proliferation, differentiation, and death. Damages to Sertoli cells cause germ cell death …