BACKGROUND Specific factors underlying successful surgical sperm retrieval rates (SRR)
or pregnancy rates (PR) after testicular sperm extraction (TESE) in adult patients with …

While 7% of the men are infertile, currently, a genetic etiology is identified in less than 25%
of those men, and 30% of the infertile men lack a definitive diagnosis, falling in the …

Intracytoplasmic sperm injection (ICSI), combined with surgical sperm retrieval (SR)
techniques, is the sole option for patients with non-obstructive azoospermia to achieve …

Context: Testicular sperm extraction (TESE) in adult patients with nonmosaic 47, XXY
provides a sperm retrieval rate (SRR) of approximately 50%. Age is the only significant …

Highlights•Identifiable genetic abnormalities contribute to 15%–20% of the most severe
forms of male infertility, azoospermia.•Klinefelter syndrome, XXY, is the most common X …

Androgen deficiency syndromes in men result from diminished production of testosterone
due to defects at one or more levels of the hypothalamic-pituitary-testicular axis …

Background The most common sex chromosomal aneuploidy in males is Klinefelter
syndrome, which is characterized by at least one supernumerary X chromosome. While …

Sex chromosome trisomies (SCT), including Klinefelter syndrome/XXY, Trisomy X, and XYY
syndrome, occur in 1 of every 500 births. The past decades of research have resulted in a …

Purpose The purpose of the study is to explore testicular sperm cryopreservation in patients
with nonobstructive azoospermia (NOA) whether affect the outcome of subsequent …

Patients with Klinefelter's syndrome experience progressive testicular degeneration
resulting in impaired endocrine function and azoospermia. What proportion of adolescents …