Pioneering research studies, beginning with those using Drosophila, have identified several
molecular and cellular mechanisms for active forgetting. The currently known mechanisms …

Dendritic spines are small, thin, specialized protrusions from neuronal dendrites, primarily
localized in the excitatory synapses. Sophisticated imaging techniques revealed that …

Small GTPases use GDP/GTP alternation to actuate a variety of functional switches that are
pivotal for cell dynamics. The GTPase switch is turned on by GEFs, which stimulate …

Stimuli that promote cell migration, such as chemokines, cytokines, and growth factors in
metazoans and cyclic AMP in Dictyostelium, activate signaling pathways that control …

The Rho family of GTPases belongs to the Ras superfamily of low molecular weight (∼ 21
kDa) guanine nucleotide binding proteins. The most extensively studied members are RhoA …

The introduction of high-resolution time lapse imaging and molecular biological tools has
changed dramatically the rate of progress towards the understanding of the complex …

The autism spectrum disorders (ASDs) are a group of conditions characterized by
impairments in reciprocal social interaction and communication, and the presence of …

The postsynaptic side of the synapse is specialized to receive the neurotransmitter signal
released from the presynaptic terminal and transduce it into electrical and biochemical …

Dendritic spines are small actin-rich protrusions from neuronal dendrites that form the
postsynaptic part of most excitatory synapses and are major sites of information processing …

Type-specific dendrite morphology is a hallmark of the neuron and has important functional
implications in determining what signals a neuron receives and how these signals are …