[HTML][HTML] Alternative Pathways in Astrobiology: Reviewing and Synthesizing Contingency and Non-Biomolecular Origins of Terrestrial and Extraterrestrial Life

K Chandru, C Potiszil, TZ Jia - Life, 2024 - mdpi.com
The pursuit of understanding the origins of life (OoL) on and off Earth and the search for
extraterrestrial life (ET) are central aspects of astrobiology. Despite the considerable efforts …

Recent progress in primitive polyester synthesis and membraneless microdroplet assembly

TZ Jia, K Chandru - Biophysics and Physicobiology, 2023 - jstage.jst.go.jp
While it is often believed that the origins of life required participation of early biomolecules, it
has been recently proposed that “non-biomolecules”, which would have been just as, if not …

Organic catalytic activity as a method for agnostic life detection

CD Georgiou, C McKay, JL Reymond - Astrobiology, 2023 - liebertpub.com
An ideal life detection instrument would have high sensitivity but be insensitive to abiotic
processes and would be capable of detecting life with alternate molecular structures. In this …

The effects of dehydration temperature and monomer chirality on primitive polyester synthesis and microdroplet assembly

R Afrin, C Chen, D Sarpa… - Macromolecular …, 2022 - Wiley Online Library
Synthesis of polyester gels via dehydration of α‐hydroxy acids (αHAs) is a plausible route to
form primitive functional polymers. αHApolyester gels assemble into membraneless droplets …

Probing the Limits of Reactant Concentration and Volume in Primitive Polyphenyllactate Synthesis and Microdroplet Assembly Processes

M Sithamparam, R Afrin, N Tharumen… - ACS Bio & Med …, 2025 - ACS Publications
Polyester microdroplets have been investigated as primitive protocell models that can
exhibit relevant primitive functions such as biomolecule segregation, coalescence, and salt …

[PDF][PDF] On the origin of life on earth.

V Soriano, R Herce - AIDS reviews, 2024 - researchgate.net
The creation of the universe out of nothing (ex nihilo) is attributable to the eternal God.
Would a direct divine intervention be needed for other singular events, such as the origin of …

The new frontier of an IOM-based panspermia hypothesis: Perspectives and feasibility: Response to commentary on “Insoluble organic matter in chondrites …

P Manini, M d'Ischia - Physics of Life Reviews, 2022 - Elsevier
We would like to thank all the commentators for their incisive but encouraging support to our
hypothesis addressing the potential involvement of the insoluble organic matter (IOM) …

Research Progress of Human Origins

R Chen, Y Liang, L Ying, Z Sabeel, X Li… - Scientific and Social …, 2023 - ojs.bbwpublisher.com
The birth of human is a miracle in earth history, and the earliest human could be traced back
to Sahelanthropus tchadensis, who had existed for at least about seven million years. In …