Aptamer-based detection of circulating targets for precision medicine

L Wu, Y Wang, X Xu, Y Liu, B Lin, M Zhang… - Chemical …, 2021 - ACS Publications
The past decade has witnessed ongoing progress in precision medicine to improve human
health. As an emerging diagnostic technique, liquid biopsy can provide real-time …

Solid-state nanochannels for bio-marker analysis

Y Huang, L Liu, C Luo, W Liu, X Lou, L Jiang… - Chemical Society …, 2023 - pubs.rsc.org
Bio-markers, such as ions, small molecules, nucleic acids, peptides, proteins and cells,
participate in the construction of living organisms and play important roles in biological …

Flexible and stretchable organic electrochemical transistors for physiological sensing devices

Y Yao, W Huang, J Chen, X Liu, L Bai… - Advanced …, 2023 - Wiley Online Library
Flexible and stretchable bioelectronics provides a biocompatible interface between
electronics and biological systems and has received tremendous attention for in situ …

Cancer biomarkers and their biosensors: A comprehensive review

H Khan, MR Shah, J Barek, MI Malik - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The article starts with a brief history of discovery of cancer biomarkers followed by statistical
data on published cancer biomarkers detection strategies in the last decade to demonstrate …

Protein glycosylation in cancer

SR Stowell, T Ju, RD Cummings - Annual Review of Pathology …, 2015 - annualreviews.org
Neoplastic transformation results in a wide variety of cellular alterations that impact the
growth, survival, and general behavior of affected tissue. Although genetic alterations …

PSA and beyond: alternative prostate cancer biomarkers

S Saini - Cellular Oncology, 2016 - Springer
Background The use of biomarkers for prostate cancer screening, diagnosis and prognosis
has the potential to improve the clinical management of the patients. Owing to inherent …

Platinum-decorated gold nanoparticles with dual functionalities for ultrasensitive colorimetric in vitro diagnostics

Z Gao, H Ye, D Tang, J Tao, S Habibi, A Minerick… - Nano Letters, 2017 - ACS Publications
Au nanoparticles (AuNPs) as signal reporters have been utilized in colorimetric in vitro
diagnostics (IVDs) for decades. Nevertheless, it remains a grand challenge to substantially …

Molecular genetics of prostate cancer: new prospects for old challenges

MM Shen, C Abate-Shen - Genes & development, 2010 - genesdev.cshlp.org
Despite much recent progress, prostate cancer continues to represent a major cause of
cancer-related mortality and morbidity in men. Since early studies on the role of the …

Nanoparticles and their applications in cell and molecular biology

EC Wang, AZ Wang - Integrative biology, 2014 - academic.oup.com
Nanoparticles can be engineered with distinctive composition, size, shape, and surface
chemistry to enable novel techniques in a wide range of biological applications. The unique …

Glycans as cancer biomarkers

B Adamczyk, T Tharmalingam, PM Rudd - Biochimica et Biophysica Acta …, 2012 - Elsevier
BACKGROUND: Non-invasive biomarkers, such as those from serum, are ideal for disease
prognosis, staging and monitoring. In the past decade, our understanding of the importance …