[HTML][HTML] Long non-coding RNAs: novel targets for nervous system disease diagnosis and therapy

IA Qureshi, MF Mehler - Neurotherapeutics, 2013 - Elsevier
The human genome encodes tens of thousands of long non-coding RNAs (lncRNAs), a
novel and important class of genes. Our knowledge of lncRNAs has grown exponentially …

The importance of long non-coding RNAs in neuropsychiatric disorders

E Hosseini, Z Bagheri-Hosseinabadi, I De Toma… - Molecular aspects of …, 2019 - Elsevier
In the last decade, transcriptome analyses have discovered thousands of long non-coding
RNAs (lncRNAs) which are assumed as a fundamental part of the gene regulatory networks …

Long noncoding RNA-directed epigenetic regulation of gene expression is associated with anxiety-like behavior in mice

PA Spadaro, CR Flavell, J Widagdo, VS Ratnu… - Biological …, 2015 - Elsevier
Background RNA-directed regulation of epigenetic processes has recently emerged as an
important feature of mammalian differentiation and development. Perturbation of this …

Integrated analysis of long non-coding RNAs (LncRNAs) and mRNA expression profiles reveals the potential role of LncRNAs in skeletal muscle development of the …

Z Li, H Ouyang, M Zheng, B Cai, P Han… - Frontiers in …, 2017 - frontiersin.org
Long non-coding RNAs (lncRNAs) play important roles in transcriptional and post-
transcriptional regulation. However, little is currently known about the mechanisms by which …

Long non-coding RNA profiling in a non-alcoholic fatty liver disease rodent model: new insight into pathogenesis

Y Chen, H Huang, C Xu, C Yu, Y Li - International journal of molecular …, 2017 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver diseases
worldwide with an unclear mechanism. Long non-coding RNAs (lncRNAs) have recently …

Current and future perspectives of noncoding RNAs in brain function and neuropsychiatric disease

EJ Kyzar, JP Bohnsack, SC Pandey - Biological psychiatry, 2022 - Elsevier
Noncoding RNAs (ncRNAs) represent the majority of the transcriptome and play important
roles in regulating neuronal functions. ncRNAs are exceptionally diverse in both structure …

Autophagy ameliorates cognitive impairment through activation of PVT1 and apoptosis in diabetes mice

Z Li, S Hao, H Yin, J Gao, Z Yang - Behavioural Brain Research, 2016 - Elsevier
The underlying mechanisms of cognitive impairment in diabetes remain incompletely
characterized. Here we show that the autophagic inhibition by 3-methyladenine (3-MA) …

Proteomic analysis of chicken skeletal muscle during embryonic development

H Ouyang, Z Wang, X Chen, J Yu, Z Li, Q Nie - Frontiers in physiology, 2017 - frontiersin.org
Embryonic growth and development of skeletal muscle is a major determinant of muscle
mass, and has a significant effect on meat production in chicken. To assess the protein …

Integrated analysis of long non-coding RNAs and mRNA expression profiles reveals the potential role of lncRNAs in gastric cancer pathogenesis

XC Lin, Y Zhu, WB Chen, LW Lin… - International …, 2014 - spandidos-publications.com
Long non-coding RNAs (lncRNAs) have been shown to play a critical role in cancer biology
and are frequently aberrantly expressed. Despite their important role in pathology, little is …

mRNA changes in nucleus accumbens related to methamphetamine addiction in mice

L Zhu, J Li, N Dong, F Guan, Y Liu, D Ma, ELK Goh… - Scientific reports, 2016 - nature.com
Methamphetamine (METH) is a highly addictive psychostimulant that elicits aberrant
changes in the expression of microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) in …