Chromosome organization in bacteria: mechanistic insights into genome structure and function
Bacterial chromosomes are folded to compact DNA and facilitate cellular processes.
Studying model bacteria has revealed aspects of chromosome folding that are applicable to …
Studying model bacteria has revealed aspects of chromosome folding that are applicable to …
Structure and function of bacterial H-NS protein
DC Grainger - Biochemical society transactions, 2016 - portlandpress.com
The histone-like nucleoid structuring (H-NS) protein is a major component of the folded
chromosome in Escherichia coli and related bacteria. Functions attributed to H-NS include …
chromosome in Escherichia coli and related bacteria. Functions attributed to H-NS include …
H-NS and RNA polymerase: a love–hate relationship?
R Landick, JT Wade, DC Grainger - Current opinion in microbiology, 2015 - Elsevier
Highlights•Similarities in the DNA binding properties of H-NS and RNA polymerase.•
Interactions between H-NS and RNA polymerase throughout the transcription cycle.•H-NS …
Interactions between H-NS and RNA polymerase throughout the transcription cycle.•H-NS …
[HTML][HTML] CD38 causes autophagic flux inhibition and cardiac dysfunction through a transcriptional inhibition pathway under hypoxia/ischemia conditions
X Zhang, L Li, Q Zhang, Q Wei, J Lin, J Jia… - Frontiers in Cell and …, 2020 - frontiersin.org
Induced autophagy is protective against myocardial hypoxia/ischemia (H/I) injury, but
evidence regarding the extent of autophagic clearance under H/I and the molecular …
evidence regarding the extent of autophagic clearance under H/I and the molecular …
Repression by H‐NS of genes required for the biosynthesis of the Vibrio cholerae biofilm matrix is modulated by the second messenger cyclic diguanylic acid
Expression of V ibrio cholerae genes required for the biosynthesis of exopolysacchide (vps)
and protein (rbm) components of the biofilm matrix is enhanced by cyclic diguanylate (c‐di …
and protein (rbm) components of the biofilm matrix is enhanced by cyclic diguanylate (c‐di …
Global H-NS counter-silencing by LuxR activates quorum sensing gene expression
RR Chaparian, MLN Tran… - Nucleic Acids …, 2020 - academic.oup.com
Bacteria coordinate cellular behaviors using a cell–cell communication system termed
quorum sensing. In Vibrio harveyi, the master quorum sensing transcription factor LuxR …
quorum sensing. In Vibrio harveyi, the master quorum sensing transcription factor LuxR …
[HTML][HTML] H-NS: an overarching regulator of the Vibrio cholerae life cycle
JC Ayala, AJ Silva, JA Benitez - Research in microbiology, 2017 - Elsevier
Vibrio cholerae has become a model organism for studies connecting virulence, pathogen
evolution and infectious disease ecology. The coordinate expression of motility, virulence …
evolution and infectious disease ecology. The coordinate expression of motility, virulence …
H-NS can facilitate specific DNA-binding by RNA polymerase in AT-rich gene regulatory regions
SS Singh, DC Grainger - PLoS genetics, 2013 - journals.plos.org
Extremely AT-rich DNA sequences present a challenging template for specific recognition by
RNA polymerase. In bacteria, this is because the promoter− 10 hexamer, the major DNA …
RNA polymerase. In bacteria, this is because the promoter− 10 hexamer, the major DNA …
Spatial organization of DNA sequences directs the assembly of bacterial chromatin by a nucleoid-associated protein
A Japaridze, S Renevey, P Sobetzko, L Stoliar… - Journal of Biological …, 2017 - ASBMB
Structural differentiation of bacterial chromatin depends on cooperative binding of abundant
nucleoid-associated proteins at numerous genomic DNA sites and stabilization of distinct …
nucleoid-associated proteins at numerous genomic DNA sites and stabilization of distinct …
Evidence for Two Different Regulatory Mechanisms Linking Replication and Segregation of Vibrio cholerae Chromosome II
T Venkova-Canova, JH Baek, PC FitzGerald… - PLoS …, 2013 - journals.plos.org
Understanding the mechanisms that coordinate replication initiation with subsequent
segregation of chromosomes is an important biological problem. Here we report two …
segregation of chromosomes is an important biological problem. Here we report two …