Pathophysiological mechanisms of liver injury in COVID‐19

AD Nardo, M Schneeweiss‐Gleixner… - Liver …, 2021 - Wiley Online Library
The recent outbreak of coronavirus disease 2019 (COVID‐19), caused by the Severe Acute
Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) has resulted in a world‐wide …

Angiotensin-converting enzyme 2: SARS-CoV-2 receptor and regulator of the renin-angiotensin system: celebrating the 20th anniversary of the discovery of ACE2

M Gheblawi, K Wang, A Viveiros, Q Nguyen… - Circulation …, 2020 - Am Heart Assoc
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that
revolve around its trivalent function: a negative regulator of the renin-angiotensin system …

Hypertension, thrombosis, kidney failure, and diabetes: is COVID-19 an endothelial disease? A comprehensive evaluation of clinical and basic evidence

C Sardu, J Gambardella, MB Morelli, X Wang… - Journal of clinical …, 2020 - mdpi.com
The symptoms most commonly reported by patients affected by coronavirus disease (COVID-
19) include cough, fever, and shortness of breath. However, other major events usually …

COVID-19, ACE2, and the cardiovascular consequences

AM South, DI Diz, MC Chappell - American Journal of …, 2020 - journals.physiology.org
The novel SARS coronavirus SARS-CoV-2 pandemic may be particularly deleterious to
patients with underlying cardiovascular disease (CVD). The mechanism for SARS-CoV-2 …

Use of renin–angiotensin–aldosterone system inhibitors and risk of COVID-19 requiring admission to hospital: a case-population study

FJ de Abajo, S Rodríguez-Martín, V Lerma… - The Lancet, 2020 - thelancet.com
Background Concerns have been raised about the possibility that inhibitors of the renin–
angiotensin–aldosterone system (RAAS) could predispose individuals to severe COVID-19; …

Hypertension, the renin–angiotensin system, and the risk of lower respiratory tract infections and lung injury: implications for COVID-19: European Society of …

R Kreutz, EAEH Algharably, M Azizi… - Cardiovascular …, 2020 - academic.oup.com
Systemic arterial hypertension (referred to as hypertension herein) is a major risk factor of
mortality worldwide, and its importance is further emphasized in the context of the novel …

Circulating plasma concentrations of angiotensin-converting enzyme 2 in men and women with heart failure and effects of renin–angiotensin–aldosterone inhibitors

IE Sama, A Ravera, BT Santema… - European heart …, 2020 - academic.oup.com
Aims The current pandemic coronavirus SARS-CoV-2 infects a wide age group but
predominantly elderly individuals, especially men and those with cardiovascular disease …

Hypertension and related diseases in the era of COVID-19: a report from the Japanese Society of Hypertension Task Force on COVID-19

S Shibata, H Arima, K Asayama, S Hoshide… - Hypertension …, 2020 - nature.com
Abstract Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2), has affected more than seven million people …

Coronaviruses pathogenesis, comorbidities and multi-organ damage–A review

K Renu, PL Prasanna, AV Gopalakrishnan - Life sciences, 2020 - Elsevier
Abstract Human coronaviruses, especially COVID-19, is an emerging pandemic infectious
disease with high morbidity and mortality. Coronaviruses are associated with comorbidities …

Role of Hypertension on the Severity of COVID-19: A Review

M Peng, J He, Y Xue, X Yang, S Liu… - Journal of …, 2021 - journals.lww.com
The novel coronavirus disease (COVID-19) caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has rapidly evolved into a global pandemic. The …