LSECs are a unique population of endothelial cells within the liver and are recognized as
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …

This Practice Guidance from the American Association for the Study of Liver Disease
(AASLD) intends to coalesce best practice recommendations for the identification of portal …

Cirrhosis is a leading cause of morbidity and mortality, impacting more than 120 million
people worldwide. Although geographic differences exist, etiologic factors such as alcohol …

Liver cirrhosis is a disease characterised by multiple complications and a poor prognosis.
The prevalence is increasing worldwide. Chronic inflammation is ongoing in liver cirrhosis …

Simvastatin is an established anti-hyperlipidemic drug and few studies have indicated its
role in the mitigation of oxidative stress. However, a systematic study considering molecular …

Statins have been used in the treatment of hyperlipidemia, both as monotherapy and in
combination therapy. Natural fermentation processes of fungi such as Monascus spp …

Clinical trials have been a central driver of change and have provided the evidence base
necessary to advance new therapies for liver diseases. This review provides a perspective …

Purpose of review To critically analyze current evidence regarding the role of statins in
cirrhosis with particular emphasis on the source of the evidence. Recent findings. Most …

Liver cirrhosis is the sequelae of chronic liver disease, accounting for 1 million deaths every
year globally. 1 Liver cirrhosis is broadly classified into 2 stages, namely compensated and …

Background: Statins can improve prognosis of patients with liver cirrhosis by suppressing
inflammation and lowering portal pressure. Here, we performed a meta-analysis to evaluate …