Flavonoids are polyphenolic compounds subdivided into 6 groups: isoflavonoids,
flavanones, flavanols, flavonols, flavones and anthocyanidins found in a variety of plants …

Numerous plant compounds and their metal-ion complexes exert antioxidative, anti-
inflammatory, anticancer, and other beneficial effects. This review highlights the different …

Cell cycle, growth, survival and metabolism are tightly regulated together and failure in
cellular regulation leads to carcinogenesis. Several signaling pathways like the PI3K, WNT …

The critical role of dysregulated epigenetic pathways in cancer genesis, development, and
therapy has typically been established as a result of scientific and technical innovations in …

Aging is one of the world's greatest concerns, requiring urgent, effective, large-scale
interventions to decrease the number of late-life chronic diseases and improve human …

The impact of dietary phytoestrogens on human health has been a topic of continuous
debate since their discovery. Nowadays, based on their presumptive beneficial effects, the …

Owing to the technological advancements, including next generation sequencing, the
significance of deregulated epigenetic mechanisms in cancer initiation, progression and …

Flavonoids, a subclass of polyphenols, have been shown to be effective against several
types of cancer, by decreasing proliferation and inducing apoptosis. Therefore, the aim of …

The dysregulation of gene expression is a critical event involved in all steps of
tumorigenesis. Aberrant histone and non-histone acetylation modifications of gene …

Cancer initiation and progression is an accumulation of genetic and epigenetic
modifications. DNA methylation is a common epigenetic modification that regulates gene …