Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

The interior of a living cell is a crowded, heterogenuous, fluctuating environment. Hence, a
major challenge in modeling intracellular transport is to analyze stochastic processes within …

One of the major challenges in modern biology is to understand how the molecular
components of a living cell operate in a highly noisy environment. What are the specific …

The dynamics of constituents and the surface response of cellular membranes—also in
connection to the binding of various particles and macromolecules to the membrane—are …

We present a general theory which allows one to accurately evaluate the mean first-passage
time (FPT) for regular random walks in bounded domains, and its extensions to related first …

Many cellular functions rely on DNA-binding proteins finding and associating to specific sites
in the genome. Yet the mechanisms underlying the target search remain poorly understood …

A molecular motor is made of either a single macromolecule or a macromolecular complex.
Just like their macroscopic counterparts, molecular motors “transduce” input energy into …

There has been a resurgence of interest in non-equilibrium stochastic processes in recent
years, driven in part by the observation that the number of molecules (genes, mRNA …

Stochastic resetting, a diffusive process whose amplitude is reset to the origin at random
times, is a vividly studied strategy to optimize encounter dynamics, eg, in chemical reactions …

Following recent discoveries of colocalization of downstream-regulating genes in living
cells, the impact of the spatial distance between such genes on the kinetics of gene product …