The field of bioinorganic chemistry is at a propitious stage of development. Ever more
complex metallobiomolecules are isolated and purified, physical methodologies and …

Zinc fingers (ZFs) are among the most structurally diverse protein domains. They interact
with nucleic acids, other proteins and lipids to facilitate a multitude of biological processes …

It is informative to detect highly conserved positions in proteins and nucleic acid
sequence/structure since they are often indicative of structural and/or functional importance …

Principles of Nucleic Acid Structure, Second Edition, provides the most complete and
concise summary of underlying principles and approaches to studying nucleic acid structure …

Chromatin immunoprecipitation (ChIP-chip and ChIP-seq) assays identify where proteins
bind throughout a genome. However, DNA contamination and DNA fragmentation …

Zinc ions are key structural components of a large number of proteins. The binding of zinc
stabilizes the folded conformations of domains so that they may facilitate interactions …

Glucose and related sugars repress the transcription of genes encoding enzymes required
for the utilization of alternative carbon sources; some of these genes are also repressed by …

Understanding how DNA binding proteins control global gene expression and chromosomal
maintenance requires knowledge of the chromosomal locations at which these proteins …

DNA Structure and Function, a timely and comprehensive resource, is intended for any
student or scientist interested in DNA structure and its biological implications. The book …

The conventional view posits that E3 ligases function primarily through conjugating ubiquitin
(Ub) to their substrate molecules. We report here that RIPLET, an essential E3 ligase in …