Antimicrobial resistance in ESKAPE pathogens
Antimicrobial-resistant ESKAPE (E nterococcus faecium, S taphylococcus aureus, K
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …
lebsiella pneumoniae, A cinetobacter baumannii, P seudomonas aeruginosa, and E …
Mobile genetic elements associated with antimicrobial resistance
SR Partridge, SM Kwong, N Firth… - Clinical microbiology …, 2018 - Am Soc Microbiol
Strains of bacteria resistant to antibiotics, particularly those that are multiresistant, are an
increasing major health care problem around the world. It is now abundantly clear that both …
increasing major health care problem around the world. It is now abundantly clear that both …
NDM metallo-β-lactamases and their bacterial producers in health care settings
W Wu, Y Feng, G Tang, F Qiao… - Clinical microbiology …, 2019 - Am Soc Microbiol
New Delhi metallo-β-lactamase (NDM) is a metallo-β-lactamase able to hydrolyze almost all
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …
β-lactams. Twenty-four NDM variants have been identified in> 60 species of 11 bacterial …
[HTML][HTML] Structure, genetics and worldwide spread of New Delhi metallo-β-lactamase (NDM): a threat to public health
Background The emergence of carbapenemase producing bacteria, especially New Delhi
metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health …
metallo-β-lactamase (NDM-1) and its variants, worldwide, has raised amajor public health …
Worldwide dissemination of the NDM‐type carbapenemases in Gram‐negative bacteria
The emergence of one of the most recently described carbapenemases, namely, the New
Delhi metallo‐lactamase (NDM‐1), constitutes a critical and growingly important medical …
Delhi metallo‐lactamase (NDM‐1), constitutes a critical and growingly important medical …
[HTML][HTML] Role of mobile genetic elements in the global dissemination of the carbapenem resistance gene blaNDM
The mobile resistance gene bla NDM encodes the NDM enzyme which hydrolyses
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …
carbapenems, a class of antibiotics used to treat some of the most severe bacterial …
Intra-and interpopulation transposition of mobile genetic elements driven by antibiotic selection
The spread of genes encoding antibiotic resistance is often mediated by horizontal gene
transfer (HGT). Many of these genes are associated with transposons, a type of mobile …
transfer (HGT). Many of these genes are associated with transposons, a type of mobile …
Genomic analysis of hospital plumbing reveals diverse reservoir of bacterial plasmids conferring carbapenem resistance
RA Weingarten, RC Johnson, S Conlan, AM Ramsburg… - MBio, 2018 - Am Soc Microbiol
The hospital environment is a potential reservoir of bacteria with plasmids conferring
carbapenem resistance. Our Hospital Epidemiology Service routinely performs extensive …
carbapenem resistance. Our Hospital Epidemiology Service routinely performs extensive …
[HTML][HTML] Large-scale network analysis captures biological features of bacterial plasmids
Many bacteria can exchange genetic material through horizontal gene transfer (HGT)
mediated by plasmids and plasmid-borne transposable elements. Here, we study the …
mediated by plasmids and plasmid-borne transposable elements. Here, we study the …
Acinetobacter baumannii transfers the blaNDM-1 gene via outer membrane vesicles
S Chatterjee, A Mondal, S Mitra… - Journal of Antimicrobial …, 2017 - academic.oup.com
Objectives: To investigate the transmission of the gene encoding New Delhi metallo-β-
lactamase-1 (bla NDM-1) through outer membrane vesicles (OMVs) released from an …
lactamase-1 (bla NDM-1) through outer membrane vesicles (OMVs) released from an …