Can we predict T cell specificity with digital biology and machine learning?

D Hudson, RA Fernandes, M Basham, G Ogg… - Nature Reviews …, 2023 - nature.com
Recent advances in machine learning and experimental biology have offered breakthrough
solutions to problems such as protein structure prediction that were long thought to be …

The vaccine world of COVID-19: India's Contribution

VP Chavda, DR Vihol, HK Solanki, V Apostolopoulos - Vaccines, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) eruption has left not
only illness and mortality in its wake, but also an overwhelming threat to health policy …

Population antibody responses following COVID-19 vaccination in 212,102 individuals

H Ward, M Whitaker, B Flower, SN Tang… - Nature …, 2022 - nature.com
Population antibody surveillance helps track immune responses to COVID-19 vaccinations
at scale, and identify host factors that may affect antibody production. We analyse data from …

mRNA vaccines against SARS-CoV-2 induce comparably low long-term IgG Fc galactosylation and sialylation levels but increasing long-term IgG4 responses …

JS Buhre, T Pongracz, I Künsting, AS Lixenfeld… - Frontiers in …, 2023 - frontiersin.org
Background The new types of mRNA-containing lipid nanoparticle vaccines BNT162b2 and
mRNA-1273 and the adenovirus-based vaccine AZD1222 were developed against SARS …

Repeated mRNA vaccination sequentially boosts SARS-CoV-2-specific CD8+ T cells in persons with previous COVID-19

ES Ford, K Mayer-Blackwell, L Jing, KJ Laing… - Nature …, 2024 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hybrid immunity is more
protective than vaccination or previous infection alone. To investigate the kinetics of spike …

Safety, tolerability, and immunogenicity of the chimpanzee adenovirus type 3-vectored Marburg virus (cAd3-Marburg) vaccine in healthy adults in the USA: a first-in …

MJ Hamer, KV Houser, AR Hofstetter, AM Ortega-Villa… - The Lancet, 2023 - thelancet.com
Background WHO has identified Marburg virus as an emerging virus requiring urgent
vaccine research and development, particularly due to its recent emergence in Ghana. We …

Immune responses following 3rd and 4th doses of heterologous and homologous COVID-19 vaccines in kidney transplant recipients

T Thomson, M Prendecki, S Gleeson, P Martin… - …, 2022 - thelancet.com
Background Solid organ transplant recipients have attenuated immune responses to SARS-
CoV-2 vaccines. In this study, we report on immune responses to 3rd-(V3) and 4th-(V4) …

Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough …

MI Azeem, AK Nooka, U Shanmugasundaram… - Blood cancer …, 2023 - AACR
Patients with multiple myeloma (MM) mount suboptimal neutralizing antibodies (nAb)
following 2 doses of SARS-CoV-2 mRNA vaccines. Currently, circulating SARS-CoV-2 …

Evidence for the heterologous benefits of prior BCG vaccination on COVISHIELD™ vaccine-induced immune responses in SARS-CoV-2 seronegative young Indian …

S Rakshit, V Adiga, A Ahmed, C Parthiban… - Frontiers in …, 2022 - frontiersin.org
This proof-of-concept study tested if prior BCG revaccination can qualitatively and
quantitively enhance antibody and T-cell responses induced by Oxford/AstraZeneca …

Immunogenicity, efficacy and safety of COVID-19 vaccines: an update of data published by 31 December 2021

K Xu, C Fan, Y Han, L Dai, GF Gao - International Immunology, 2022 - academic.oup.com
The unprecedented coronavirus disease 2019 (COVID-19) pandemic has caused a disaster
for public health in the last 2 years, without any sign of an ending. Various vaccines were …