Studies of local adaptation provide important insights into the power of natural selection
relative to gene flow and other evolutionary forces. They are a paradigm for testing …

Life-history traits or “fitness components”—such as age and size at maturity, fecundity and
fertility, age-specific rates of survival, and life span—are the major phenotypic determinants …

There is a growing appreciation that chromosome inversions affect rates of adaptation,
speciation, and the evolution of sex chromosomes. Comparative genomic studies have …

A central challenge in evolutionary biology is to identify genes underlying ecologically
important traits and describe the fitness consequences of naturally occurring variation at …

The National Research Council issued a report in 2009 that heavily criticized the forensic
sciences. The report made several recommendations that if addressed would allow the …

Inversions are structural mutations that reverse the sequence of a chromosome segment
and reduce the effective rate of recombination in the heterozygous state. They play a major …

Understanding the genetic underpinnings of adaptive change is a fundamental but largely
unresolved problem in evolutionary biology. D rosophila melanogaster, an ancestrally …

Most adaptation is thought to occur through the fixation of numerous alleles at many different
loci. Consequently, the independent evolution of similar phenotypes is predicted to occur …

Clines in chromosomal inversion polymorphisms—presumably driven by climatic gradients—
are common but there is surprisingly little evidence for selection acting on them. Here we …

The maternal transmission of mitochondrial genomes invokes a sex-specific selective sieve,
whereby mutations in mitochondrial DNA can only respond to selection acting directly on …