Glutathione and infection

D Morris, M Khurasany, T Nguyen, J Kim… - … et Biophysica Acta (BBA …, 2013 - Elsevier
BACKGROUND: The tripeptide γ-glutamylcysteinylglycine or glutathione (GSH) has
demonstrated protective abilities against the detrimental effects of oxidative stress within the …

Programmed cell death pathways as targets for developing antifilarial drugs: Lessons from the recent findings

NC Das, P Chakraborty, S Nandy, A Dey… - Journal of Cellular …, 2023 - Wiley Online Library
More than half a century has passed since the introduction of the National Filariasis Control
Program; however, as of 2023, lymphatic filariasis (LF) still prevails globally, particularly in …

Anthelmintic Potential of Thymoquinone and Curcumin on Fasciola gigantica

R Ullah, A Rehman, MF Zafeer, L Rehman, YA Khan… - PloS one, 2017 - journals.plos.org
Fasciolosis an economically important global disease of ruminants in the temperate and
tropical regions, caused by Fasciola hepatica and F. gigantica, respectively, also poses a …

Evidence of reactive oxygen species (ROS) mediated apoptosis in Setaria cervi induced by green silver nanoparticles from Acacia auriculiformis at a very low dose

P Saini, SK Saha, P Roy, P Chowdhury… - Experimental …, 2016 - Elsevier
Green synthesis of silver nanomaterial plays a pivotal role in the growing field of
nanotechnology. Development of anti-parasitic drugs from plant metabolites has been in …

Curcumin Generates Oxidative Stress and Induces Apoptosis in Adult Schistosoma mansoni Worms

D de Paula Aguiar, M Brunetto Moreira Moscardini… - PLoS …, 2016 - journals.plos.org
Inducing apoptosis is an interesting therapeutic approach to develop drugs that act against
helminthic parasites. Researchers have investigated how curcumin (CUR), a biologically …

Phenolics and terpenoids; the promising new search for anthelmintics: a critical review

N Mukherjee, S Mukherjee, P Saini… - Mini reviews in …, 2016 - ingentaconnect.com
Ailments caused by helminth parasites are global causing different types of clinical
complications with permanent and long term morbidity in humans. Although huge advances …

Thymoquinone Induced Leishmanicidal Effect via Programmed Cell Death in Leishmania donovani

M Islamuddin, A Ali, O Afzal, A Ali, I Ali… - ACS …, 2022 - ACS Publications
Visceral leishmaniasis (VL) or kala-azar is a vector-borne dreaded protozoal infection that is
caused by the parasite Leishmania donovani. With increases in the dramatic infection rates …

Chitosan biopolymer functionalized gold nanoparticles with controlled cytotoxicity and improved antifilarial efficacy

P Chowdhury, B Roy, N Mukherjee… - … Composites and Hybrid …, 2018 - Springer
Ultra-high stable chitosan functionalized gold nanoparticles (GNPs) of desired biopolymeric
corona are synthesized without adding conventional hazardous reducing agents. The …

Antifilarial effects of polyphenol rich ethanolic extract from the leaves of Azadirachta indica through molecular and biochemical approaches describing reactive oxygen …

N Mukherjee, S Mukherjee, P Saini, P Roy… - Experimental …, 2014 - Elsevier
Lymphatic filariasis, a global cause of morbidity needs much more attention in developing
potent therapeutics that can be effective against both microfilariae (mf) and adults. Efficient …

Trichinella spiralis: A new parasitic target for curcumin nanoformulas in mice models

SI Khedr, MM Gomaa, NMFH Mogahed… - Parasitology …, 2024 - Elsevier
Trichinosis spiralis is a global disease with significant economic impact. Albendazole is the
current-treatment. Yet, the world-widely emerging antimicrobial resistance necessitates …