Puberty initiates cascading relationships between neurodevelopmental, social, and internalizing processes across adolescence

JH Pfeifer, NB Allen - Biological Psychiatry, 2021 - Elsevier
Adolescence is a period of dramatic developmental transitions—from puberty-related
changes in hormones, bodies, and brains to an increasingly complex social world. The …

[HTML][HTML] Brain-based sex differences in depression: a systematic review of neuroimaging studies

S Mohammadi, H Seyedmirzaei, MA Salehi… - Brain Imaging and …, 2023 - Springer
Major depressive disorder (MDD) is a common psychiatric illness with a wide range of
symptoms such as mood decline, loss of interest, and feelings of guilt and worthlessness …

Reduced hippocampal and amygdala volume as a mechanism underlying stress sensitization to depression following childhood trauma

DG Weissman, HK Lambert, AM Rodman… - Depression and …, 2020 - Wiley Online Library
Background Stressful life events are more likely to trigger depression among individuals
exposed to childhood adversity. However, the mechanisms underlying this stress …

[HTML][HTML] Psychobiological risk factors for suicidal thoughts and behaviors in adolescence: a consideration of the role of puberty

TC Ho, AJ Gifuni, IH Gotlib - Molecular psychiatry, 2022 - nature.com
Suicide is the second leading cause of death among adolescents. While clinicians and
researchers have begun to recognize the importance of considering multidimensional …

[HTML][HTML] Contributions of emotion regulation and brain structure and function to adolescent internalizing problems and stress vulnerability during the COVID-19 …

DG Weissman, AM Rodman, ML Rosen… - … psychiatry global open …, 2021 - Elsevier
Background Adolescence is a period of increased vulnerability for internalizing problems,
particularly following stressful life events. We examined how emotion regulation and brain …

[HTML][HTML] Androgens and the developing hippocampus

KE Kight, MM McCarthy - Biology of sex differences, 2020 - Springer
The hippocampus is central to spatial learning and stress responsiveness, both of which
differ in form and function in males versus females, yet precisely how the hippocampus …

[HTML][HTML] Associations between multi-method latent factors of puberty and brain structure in adolescent girls

ML Byrne, N Vijayakumar, SJ Chavez… - Developmental …, 2023 - Elsevier
Pubertal processes are associated with structural brain development, but studies have
produced inconsistent findings that may relate to different measurements of puberty …

Testosterone and hippocampal trajectories mediate relationship of poverty to emotion dysregulation and depression

DM Barch, EA Shirtcliff, NM Elsayed… - Proceedings of the …, 2020 - National Acad Sciences
There is robust evidence that early poverty is associated with poor developmental outcomes,
including impaired emotion regulation and depression. However, the specific mechanisms …

[HTML][HTML] DHEAS and human development: an evolutionary perspective

B Campbell - Frontiers in Endocrinology, 2020 - frontiersin.org
Adrenarche, the post-natal rise of DHEA and DHEAS, is unique to humans and the African
Apes. Recent findings have linked DHEA in humans to the development of the left …

[HTML][HTML] The effects of puberty and its hormones on subcortical brain development

N Vijayakumar, G Youssef, NB Allen… - Comprehensive …, 2021 - Elsevier
Puberty triggers a period of structural “re-organization” in the brain, when rising hormone
levels act via receptors to influence morphology. However, our understanding of these …