This review focuses on recent advances in the development and use of bioactive glass for
tissue engineering applications. Despite its inherent brittleness, bioactive glass has several …

The repair and regeneration of large bone defects resulting from disease or trauma remains
a significant clinical challenge. Bioactive glass has appealing characteristics as a scaffold …

Vascularization remains a critical challenge in tissue engineering. The development of
vascular networks within densely populated and metabolically functional tissues facilitate …

Tissue engineering plays an important role in the production of skin equivalents for the
therapy of chronic and especially burn wounds. Actually, there exists no (cellularized) skin …

Current limitations of exogenous scaffolds or extracellular matrix based materials have
underlined the need for alternative tissue-engineering solutions. Scaffolds may elicit …

Advances in cell culture methods, multidisciplinary research, clinical need to replace lost
skin tissues and regulatory need to replace animal models with alternative test methods has …

This paper describes a method for fabricating perfusable vascular channels coated with
endothelial cells within a cultured skin-equivalent by fixing it to a culture device connected to …

Tissue engineering can be used to restore, maintain, or enhance tissues and organs. The
potential impact of this field, however, is far broader—in the future, engineered tissues could …

Significant progress has been made over the years in the development of in vitro-
engineered substitutes that mimic human skin, either to be used as grafts for the …

Tissue engineering is currently limited by the inability to adequately vascularize tissues in
vitro or in vivo. Issues of nutrient perfusion and mass transport limitations, especially oxygen …