Occlusive arterial disease is a leading cause of morbidity and mortality worldwide. Aside
from balloon angioplasty, bypass graft surgery is the most commonly performed …

Angiogenesis is a process associated with the migration and proliferation of endothelial
cells (EC) to form new blood vessels. It is involved in various physiological and …

The plasminogen system has been implicated in clot lysis, wound healing, tissue
regeneration, cancer and many other processes that affect health and disease. The …

Intimal thickening, the accumulation of cells and extracellular matrix within the inner vessel
wall, is a physiological response to mechanical injury, increased wall stress, or chemical …

Activation of the fibrinolytic system is dependent on the conversion of the plasma zymogen,
plasminogen (Pg), to the serine protease plasmin (Pm) by the physiological activators …

During atheromatous plaque formation or restenosis after angioplasty, smooth muscle cells
(SMCs) migrate from the media toward the intima, where they proliferate and undergo …

The molecular mechanisms predisposing to atherosclerotic aneurysm formation remain
undefined% 1, 5. Nevertheless, rupture of aortic aneurysms is a major cause of death in …

Vascular remodeling, defined as lasting structural changes in the vessel wall in response to
hemodynamic stimuli, plays a role in many (patho) physiological processes requiring cell …

The urokinase-type plasminogen activator (uPA), its inhibitor PA I-1 and its cellular receptor
(uPAR), play a pivotal role in pericellular proteolysis. In addition, through their interactions …

Objective: Recent evidence indicates that preeclampsia is associated with the presence of
autoantibodies capable of activating the angiotensin II receptor, AT1. We sought to evaluate …