Autoimmune myasthenia gravis (MG) is characterized by muscle weakness caused by
antibodies directed against proteins of the neuromuscular junction. The main antigenic …

The thymus plays distinct roles in the pathogenesis of the different Myasthenia gravis (MG)
subtypes. Inflammatory, neoplastic and age-related alterations of the thymus are of pivotal …

Objective Hypothyroidism has multiple etiologies and manifestations. Appropriate treatment
requires an accurate diagnosis and is influenced by coexisting medical conditions. This …

Background Chronic mucocutaneous candidiasis (CMC) is characterized by susceptibility to
candida infection of skin, nails, and mucous membranes. Patients with recessive CMC and …

Most patients with autoimmune polyendocrine syndrome type I (APS-I) display chronic
mucocutaneous candidiasis (CMC). We hypothesized that this CMC might result from …

Chronic mucocutaneous candidiasis (CMC) is frequently associated with T cell
immunodeficiencies. Specifically, the proinflammatory IL-17A–producing Th17 subset is …

Anti-cytokine autoantibodies (ACAAs) are increasingly recognized as modulating disease
severity in infection, inflammation and autoimmunity. By reducing or augmenting cytokine …

Autoimmune polyendocrine syndrome type I (APS‐I) is a monogenic model disease of
autoimmunity. Its hallmarks are chronic mucocutaneous candidosis, hypoparathyroidism …

The discovery of the autoimmune regulator (AIRE) protein and the delineation of its critical
contributions in the establishment of central immune tolerance has significantly expanded …

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), also known
as autoimmune polyglandular syndrome type-1 (APS-1), is a rare monogenic autoimmune …