Iron deficiency and blood donation: links, risks and management

E Mantadakis, P Panagopoulou… - Journal of Blood …, 2022 - Taylor & Francis
The purpose of this review is to raise awareness about the frequently underappreciated
association of blood donation with iron deficiency, and to describe methods for its prevention …

A randomized, blinded, placebo‐controlled trial of education and iron supplementation for mitigation of iron deficiency in regular blood donors

AE Mast, W Bialkowski, BJ Bryant, DJ Wright… - …, 2016 - Wiley Online Library
BACKGROUND The historical approach of offering dietary advice to donors with low
hemoglobin (Hb) is ineffective for preventing iron deficiency in frequent donors. Alternative …

Frequent blood donations alter susceptibility of red blood cells to storage‐and stress‐induced hemolysis

T Kanias, M Stone, GP Page, Y Guo… - …, 2019 - Wiley Online Library
BACKGROUND Frequent whole blood donations increase the prevalence of iron depletion
in blood donors, which may subsequently interfere with normal erythropoiesis. The purpose …

Evaluating the clinical effect of female blood donors of child-bearing age on maternal and neonatal outcomes: a cohort study

M Chassé, A Tinmouth, M Goldman, SF O'Brien… - Transfusion Medicine …, 2020 - Elsevier
Iron deficiency is a global problem in women of child-bearing age and is associated with
adverse maternal and newborn outcomes. Repeated blood donations deplete iron stores …

Impact of donor ferritin testing on iron deficiency prevention and blood availability in France: a cohort simulation study

P Richard, AM Fillet, L Malard, C Leclerc… - Vox …, 2023 - Wiley Online Library
Abstract Background and Objectives Implementing a ferritin testing policy for whole blood
(WB) donors may prevent iron deficiency (ID, ferritin< 26 ng/mL) and anaemia, but may …

Estimates of total body iron indicate 19 mg and 38 mg oral iron are equivalent for the mitigation of iron deficiency in individuals experiencing repeated phlebotomy

W Bialkowski, JE Kiss, DJ Wright… - American journal of …, 2017 - Wiley Online Library
Iron deficiency anemia is a common clinical condition often treated with tablets containing
65 mg of elemental iron. Such doses can elicit gastrointestinal side effects lowering patient …

The operational implications of donor behaviors following enrollment in STRIDE (Strategies to Reduce Iron Deficiency in blood donors)

RG Cable, RJ Birch, BR Spencer, DJ Wright… - …, 2017 - Wiley Online Library
BACKGROUND Donor behaviors in STRIDE (Strategies to Reduce Iron Deficiency), a trial to
reduce iron deficiency, were examined. STUDY DESIGN AND METHODS Six hundred …

Serum ferritin in plateletpheresis and whole blood donors

F Duggan, K O'Sullivan, JP Power, M Healy… - … and Apheresis Science, 2016 - Elsevier
Abstract Background and Objectives We performed a prospective analysis of iron status in
plateletpheresis donors, using whole blood donors as a control group, to assess the …

[HTML][HTML] High-dose intravenous versus oral iron in blood donors with iron deficiency: the IronWoMan randomized, controlled clinical trial

C Drexler, S Macher, I Lindenau, M Holter, M Moritz… - Clinical Nutrition, 2020 - Elsevier
Introduction Frequent blood donation often leads to iron deficiency and even anemia but
appropriate strategies for detection and prevention are currently not mandatory. At the …

[HTML][HTML] Iron-deficient erythropoiesis in blood donors and red blood cell recovery after transfusion: initial studies with a mouse model

S Bandyopadhyay, GM Brittenham, RO Francis… - Blood …, 2017 - ncbi.nlm.nih.gov
Background Most frequent red cell (RBC) donors and many first-time donors are iron
deficient, but meet haemoglobin standards. However, the effects of donation-induced iron …