Transient receptor potential (TRP) channels are sensors for a variety of cellular and
environmental signals. Mammals express a total of 28 different TRP channel proteins, which …

The pleiotropic cytokine interleukin-6 (IL-6) is emerging as a molecule with both beneficial
and destructive potentials. It can exert opposing actions triggering either neuron survival …

Nerve hydrodissection (HD), a technique used when treating nerve entrapments, involves
the injection of an anesthetic, saline, or 5% dextrose in water to separate the nerve from the …

According to the International Association for the Study of Pain (IASP) pain is characterized
as an “unpleasant sensory and emotional experience associated with actual or potential …

Pain is associated with several conditions, such as inflammation, that result from altered
peripheral nerve properties. Electroacupuncture (EA) is a common Chinese clinical medical …

Chemotherapy-induced neuropathic pain (CINP) is among the most common clinical
complications associated with the use of anti-cancer drugs. CINP occurs in nearly 68.1% of …

Acupuncture, as a traditional treatment, has been extensively used in China for thousands of
years. According to the World Health Organization (WHO), acupuncture is recommended for …

Patients with peripheral nerve injuries would highly likely suffer from chronic neuropathic
pain even after surgical intervention. The primary reasons for this involve sustained …

Neuropathic pain in humans results from an injury or disease of the somatosensory nervous
system at the peripheral or central level. Despite the considerable progress in pain …

A fundamental subdivision of nociceptive sensory neurons is named after their unique
sensitivity to capsaicin, the pungent ingredient in hot chili peppers: these are the capsaicin …