Astrocytes in selective vulnerability to neurodegenerative disease
Selective vulnerability of specific brain regions and cell populations is a hallmark of
neurodegenerative disorders. Mechanisms of selective vulnerability involve neuronal …
neurodegenerative disorders. Mechanisms of selective vulnerability involve neuronal …
A concerted neuron–astrocyte program declines in ageing and schizophrenia
E Ling, J Nemesh, M Goldman, N Kamitaki, N Reed… - Nature, 2024 - nature.com
Human brains vary across people and over time; such variation is not yet understood in
cellular terms. Here we describe a relationship between people's cortical neurons and …
cellular terms. Here we describe a relationship between people's cortical neurons and …
Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting
Astrocytes are emerging as key regulators of cognitive function and behavior. This review
highlights some of the latest advances in the understanding of astrocyte roles in different …
highlights some of the latest advances in the understanding of astrocyte roles in different …
Sleep architecture and vitamin D in hypertensives with obstructive sleep apnea: A polysomnographic study
J Kanclerska, M Wieckiewicz… - Dental and …, 2024 - bazawiedzy.upwr.edu.pl
Background. Obstructive sleep apnea (OSA) and arterial hypertension (AH) are closely
linked disorders with common pathophysiological features. Objectives. The present study …
linked disorders with common pathophysiological features. Objectives. The present study …
Norepinephrine Signals Through Astrocytes To Modulate Synapses
KB Lefton, Y Wu, A Yen, T Okuda, Y Zhang, Y Dai… - …, 2024 - pmc.ncbi.nlm.nih.gov
Locus coeruleus (LC)-derived norepinephrine (NE) drives network and behavioral
adaptations to environmental saliencies by reconfiguring circuit connectivity, but the …
adaptations to environmental saliencies by reconfiguring circuit connectivity, but the …
Astrocytes: new evidence, new models, new roles
Astrocytes have been in the limelight of active research for about 3 decades now. Over this
period, ideas about their function and role in the nervous system have evolved from simple …
period, ideas about their function and role in the nervous system have evolved from simple …
[HTML][HTML] Astrocytic chloride regulates brain function in health and disease
V Untiet - Cell Calcium, 2024 - Elsevier
Chloride ions (Cl−) play a pivotal role in synaptic inhibition in the central nervous system,
primarily mediated through ionotropic mechanisms. A recent breakthrough emphathizes the …
primarily mediated through ionotropic mechanisms. A recent breakthrough emphathizes the …
[HTML][HTML] Lifestyle Factors Counteract the Neurodevelopmental Impact of Genetic Risk for Accelerated Brain Aging in Adolescence
Background The transition from childhood to adolescence is characterized by enhanced
neural plasticity and a consequent susceptibility to both beneficial and adverse aspects of …
neural plasticity and a consequent susceptibility to both beneficial and adverse aspects of …
[HTML][HTML] Dynamic changes of media prefrontal cortex astrocytic activity in response to negative stimuli in male mice
AM Wu, JY Zhang, WZ Lun, Z Geng, Y Yang, JC Wu… - Neurobiology of …, 2024 - Elsevier
Astrocytes play significant roles in regulating the central stress response. Chronic stress
impairs the structure and function of astrocytes in many brain regions such as media …
impairs the structure and function of astrocytes in many brain regions such as media …
Cortical norepinephrine-astrocyte signaling critically mediates learned behavior
Updating behavior based on feedback from the environment is a crucial means by which
organisms learn and develop optimal behavioral strategies. Norepinephrine (NE) release …
organisms learn and develop optimal behavioral strategies. Norepinephrine (NE) release …