Some patients remain unwell for months after “recovering” from the acute COVID-19. They
develop persistent fatigue, cognitive problems, headaches, disrupted sleep, myalgias and …

Exercise has long been known for its active role in improving physical fitness and sustaining
health. Regular moderate-intensity exercise improves all aspects of human health and is …

Exercise is considered an important component of effective chronic pain management and it
is well-established that long-term exercise training provides pain relief. In healthy, pain-free …

Exercise and physical activity is recommended treatment for a wide range of chronic pain
conditions. In addition to several well-documented effects on physical and mental health, 8 …

We propose a framework for understanding and interpreting the pathophysiology of Myalgic
Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) that considers wider determinants …

Oxidative stress can be induced by various stimuli and altered in certain conditions,
including exercise and pain. Although many studies have investigated oxidative stress in …

Abstract Purpose of Review The autonomic nervous system is an important regulator of
stress responses and exhibits functional changes in chronic pain states. This review …

Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a complex
condition with no reliable diagnostic biomarkers. Studies have shown evidence of …

Objective Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and fibromyalgia
(FM) are two debilitating, moderately comorbid illnesses in which chronic musculoskeletal …

Despite the established efficacy and effectiveness of Spinal Cord Stimulation (SCS), there is
still no consensus on the supraspinal mechanisms of action of this therapy. The purpose of …