The basal ganglia are a chain of subcortical nuclei that facilitate action selection. Two striatal
projection systems—so-called direct and indirect pathways—form the functional backbone of …

Dopamine shapes a wide variety of psychomotor functions. This is mainly accomplished by
modulating cortical and thalamic glutamatergic signals impinging upon principal medium …

Salient stimuli redirect attention and suppress ongoing motor activity. This attentional shift is
thought to rely upon thalamic signals to the striatum to shift cortically driven action selection …

The striatum plays a central role in motor control and motor learning. Appropriate responses
to environmental stimuli, including pursuit of reward or avoidance of aversive experience all …

The imbalance between cholinergic activity and dopaminergic activity in the striatum causes
a variety of neurological disorders, such as Parkinson's disease. During sensorimotor …

Striatal cholinergic interneurons (ChIs) are central for the processing and reinforcement of
reward‐related behaviors that are negatively affected in states of altered dopamine …

The purpose of this review is to bridge the gap between earlier literature on striatal
cholinergic interneurons and mechanisms of microcircuit interaction demonstrated with the …

The degeneration of mesencephalic dopaminergic neurons that innervate the basal ganglia
is responsible for the cardinal motor symptoms of Parkinson's disease (PD). It has been …

In recent years, there has been a great deal of progress toward understanding the role of the
striatum and dopamine in action selection. The advent of new animal models and the …

Striatal cholinergic interneurons are pivotal modulators of the striatal circuitry involved in
action selection and decision making. Although nicotinic receptors are important transducers …