Metabolic reprogramming, including enhanced biosynthesis of macromolecules, altered
energy metabolism, and maintenance of redox homeostasis, is considered a hallmark of …

During oncogenesis, cells become unrestrictedly proliferative thereby altering the tissue
homeostasis and resulting in subsequent hyperplasia. This process is paralleled by …

Iron overload triggers the ferroptosis in the heart following ischemia/reperfusion (I/R) and
transferrin receptor 1 (TfR1) charges the cellular iron uptake. Bioinformatics analysis shows …

Cisplatin (CDDP)-based chemotherapy is the first-line treatment for muscle-invasive and
metastatic bladder cancer, yet most patients rapidly develop resistance. N6 …

Introduction Ferroptosis, a newly identified type of programmed cell death type, has been
proven to contribute to the progression of myocardial ischemia/reperfusion (I/R) injury …

The serine synthesis pathway (SSP) involving metabolic enzymes phosphoglycerate
dehydrogenase (PHGDH), phosphoserine aminotransferase 1 (PSAT1), and phosphoserine …

The mutation of TP53 gene affects half of all human cancers, resulting in impairment of the
regulation of several cellular functions, including cell cycle progression and cell death in …

The pathophysiology of coronavirus disease 2019 (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), and especially of its complications is still …

Dysfunction of p53 is observed in many malignant tumors, which is related to cancer
susceptibility. In cervical cancer, p53 is primarily degradated through the complex of high …

Long noncoding RNAs (lncRNAs) play an important role in the progression of hepatocellular
carcinoma (HCC). Linc01612 is a novel lncRNA that function remains unknown in the …